... sets are essentially non-overlapping. The Wnt pathway activates key genes of all three germ layers, including pair-rule genes, and Tc-caudal and Tc-twist . Furthermore, the Wnt pathway is required for hindgut development and we identify Tc-senseless as a novel hindgut patterning gene required...

... in the single Drosophila RbAp46/RbAp48 homolog Caf1, identified as strong suppressors of a senseless overexpression phenotype. Reduced levels of Caf1 expression result in flies with phenotypes reminiscent of Hox gene misregulation. Additionally, analysis of Caf1 mutant tissue suggests that Caf1 plays important...

... zinc-finger transcription factor senseless ( sens ) in the developing R2,5 precursors to block ectopic R8 differentiation. Our results support a new model for R8 selection in which lateral inhibition establishes a transient pattern of selected R8s that is permanently reinforced by a repressive bistable...

...Melih Acar; Hamed Jafar-Nejad; Nikolaos Giagtzoglou; Sasidhar Yallampalli; Gabriela David; Yuchun He; Christos Delidakis; Hugo J. Bellen The zinc-finger transcription factor Senseless is co-expressed with basic helix-loop-helix (bHLH) proneural proteins in Drosophila sensory organ precursors...

... is instead under the control of the transcription factor Senseless. We show that high levels of Egfr activation are incompatible with R8 differentiation and describe the mechanism by which Egfr signaling is actively prevented in R8. Specifically,Senseless does not affect cytoplasmic transduction of Egfr...

...Vidya Chandrasekaran; Steven K. Beckendorf Apoptosis in developing Drosophila embryos is rare and confined to specific groups of cells. We explain how one organ, salivary glands, of Drosophila embryos avoids apoptosis. senseless ( sens ), a Zn-finger transcription factor, is expressed...

... the SOP insensitive to Dl. * Author for correspondence (e-mail: [email protected] ) 30 1 2003 © 2003. 2003 Suppressor of Hairless Enhancer of split complex Notch-signalling Bristle development Presenilin Kuzbanian Senseless Notch signalling plays a fundamental...

... , a second mouse homolog, play pivotal roles in blood cell lineage differentiation. However, neither Gfi1 nor Gfi1b has been implicated in nervous system development, even though their invertebrate homologues, senseless in Drosophila and pag-3 in C. elegans are expressed and required in the nervous system...