... for multiple rounds of DNA replication, likely via endocycles, in trophoblast giant cells. Furthermore, MYC supports the expression of DNA replication and nucleotide biosynthesis genes along with ribosomal RNA. Increased DNA damage and senescence occur in trophoblast giant cells without Myc , accompanied...

...Vishnu Mishra; Archita Singh; Nidhi Gandhi; Shabari Sarkar Das; Sandeep Yadav; Ashutosh Kumar; Ananda K. Sarkar ABSTRACT The submergence-induced hypoxic condition negatively affects the plant growth and development, and causes early onset of senescence. Hypoxia alters the expression of a number...

... of MAX2 in some tissues. Like REV, MAX2 plays known roles in the control of plant architecture, photobiology and senescence, which prompted us to initiate a multi-level analysis of growth phenotypes of hd-zipIII , max2 and respective higher order mutants thereof. Our data suggest a complex relationship...

...Muriel Rhinn; Birgit Ritschka; William M. Keyes ABSTRACT Cellular senescence is a state comprising an essentially irreversible proliferative arrest combined with phenotypic changes and pronounced secretory activity. Although senescence has long been linked with aging, recent studies have uncovered...

... ). References Allu , A. D. , Soja , A. M. , Wu , A. , Szymanski , J. and Balazadeh , S. ( 2014 ). Salt stress and senescence: identification of cross-talk regulatory components . J. Exp. Bot.   65 , 3993 - 4008 . 10.1093/jxb/eru173 Arsova , B. , Hoja , U...

... of gene inactivation and reactivation during this continuous process of senescence and budding. During senescence, the zooidal epidermis showed acid β-galactosidase activity, lost proliferating cell nuclear antigen immunoreactivity and became ultrastructurally worn, indicating that the epidermis...

... (MEFs), and mutant MEFs also display diminished replicative capacity in culture, leading to premature senescence. Replicative senescence in MEFs is classically triggered by products of the Ink4a ( Cdkn2a ) gene. However, this Ink4a pathway is not activated during senescence of Zeb1 mutant MEFs. Instead...

...Christine M. Ellis; Punita Nagpal; Jeffery C. Young; Gretchen Hagen; Thomas J. Guilfoyle; Jason W. Reed In plants, both endogenous mechanisms and environmental signals regulate developmental transitions such as seed germination, induction of flowering,leaf senescence and shedding of senescent...