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Keywords: Second heart field
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Journal: Development
Development (2018) 145 (22): dev167510.
Published: 21 November 2018
... , C. E. and Burns , C. G. ( 2013 ). Zebrafish second heart field development relies on progenitor specification in anterior lateral plate mesoderm and nkx2.5 function . Development   140 , 1353 - 1363 . 10.1242/dev.088351 Hami , D. , Grimes , A. C. , Tsai , H.-J...
Includes: Supplementary data
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Journal: Development
Development (2015) 142 (11): 2037–2047.
Published: 1 June 2015
... CASZ1 is expressed in murine cardiomyocytes. Genetic fate mapping with an inducible Casz1 allele demonstrates that CASZ1-expressing cells give rise to cardiomyocytes in the first and second heart fields. We show through the generation of a cardiac conditional null mutation that Casz1 is essential...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (10): 1767–1776.
Published: 15 May 2015
.... Published by The Company of Biologists Ltd 2015 SUMMARY: The study of zebrafish embryos deficient for Gpc4 reveals that it is essential for efficient cardiomyocyte differentiation, providing insights into how mutations in glypicans can cause congenital heart defects. Second heart field Wnt...
Includes: Supplementary data
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Journal: Development
Development (2014) 141 (16): 3112–3122.
Published: 15 August 2014
.... Proliferation assays reveal that hand2 can impact cardiomyocyte production by promoting division of late-differentiating cardiac progenitors within the second heart field. Additionally, our data suggest that hand2 can influence cardiomyocyte production by altering the patterning of the anterior lateral plate...
Includes: Supplementary data
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Journal: Development
Development (2011) 138 (11): 2389–2398.
Published: 1 June 2011
... located medially relative to atrial progenitors ( Schoenebeck et al., 2007 ). The portion of the heart field that gives rise to the initial heart tube has been called the first heart field, whereas the second heart field is added later. In mouse, these two populations of cardiac progenitors...
Includes: Supplementary data
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Journal: Development
Development (2009) 136 (10): 1761–1770.
Published: 15 May 2009
... that Hedgehog (Hh) signaling marked a subset of cardiac progenitors specific to the atrial septum and the pulmonary trunk in the mouse. Using genetic inducible fate mapping with Gli1 CreERT2 , we marked Hh-receiving progenitors in anterior and posterior second heart field splanchnic mesoderm between E8 and E10...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (9): 1465–1474.
Published: 1 May 2009
...Tessa Peterkin; Abigail Gibson; Roger Patient Over the past few years it has become clear that over half of the mammalian heart derives from outside the heart field as originally defined. Such a second heart field, however, has not been described in zebrafish, which could explain its smaller, two...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (2): 317–326.
Published: 15 January 2009
... that Isl1 demarcates a separate cardiac lineage, also called the second heart field( Cai et al., 2003 ) (reviewed by Buckingham et al., 2005 ; Abu-Issa and Kirby, 2007 ). However, in vitro studies in cell culture systems and analysis of Xenopus Isl1 implicate that Isl1 is part of the early...
Includes: Supplementary data