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Keywords: Sec23a
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Journal Articles
Smrita Chaudhury, Kazuhide S. Okuda, Katarzyna Koltowska, Anne K. Lagendijk, Scott Paterson, Gregory J. Baillie, Cas Simons, Kelly A. Smith, Benjamin M. Hogan, Neil I. Bower
Journal:
Development
Development (2020) 147 (18): dev190983.
Published: 18 September 2020
... migration through the embryo. Using a forward genetic screen, we identified mbtps1 and sec23a , components of the COP-II protein secretory pathway, as essential for developmental lymphangiogenesis. In both mutants, LECs initially depart the cardinal vein but then fail in their ongoing migration. A key cargo...
Includes: Supplementary data