1-20 of 21
Keywords: Salivary gland
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development (2020) 147 (19): dev192807.
Published: 09 October 2020
...Ninche Ninche; Mingyu Kwak; Soosan Ghazizadeh ABSTRACT Salivary glands exert exocrine secretory function to provide saliva for lubrication and protection of the oral cavity. Its epithelium consists of several differentiated cell types, including acinar, ductal and myoepithelial cells, that are...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (21): dev166363.
Published: 05 November 2018
...Alison J. May; Noel Cruz-Pacheco; Elaine Emmerson; Eliza A. Gaylord; Kerstin Seidel; Sara Nathan; Marcus O. Muench; Ophir D. Klein; Sarah M. Knox ABSTRACT The ductal system of the salivary gland has long been postulated to be resistant to radiation-induced damage, a common side effect incurred by...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (15): dev164822.
Published: 02 August 2018
...Melissa A. Metzler; Swetha Raja; Kelsey H. Elliott; Regina M. Friedl; Nhut Quang Huy Tran; Samantha A. Brugmann; Melinda Larsen; Lisa L. Sandell ABSTRACT In mammals, the epithelial tissues of major salivary glands generate saliva and drain it into the oral cavity. For submandibular salivary glands...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (3): dev157115.
Published: 13 February 2018
.... Endomitotic cells attain a higher ploidy and larger size than endocycling cells, and endomitotic SPG are necessary for the blood-brain barrier. Decreased Notch signaling promotes endomitosis even in the ventral nerve cord SPG that normally are mononucleate, but not in the endocycling salivary gland cells...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (13): 2311–2324.
Published: 01 July 2016
... signaling controls epithelial morphogenetic changes and differentiation using the salivary gland as a model. Experiments using genetically manipulated mice and organ cultures revealed that WNT signaling at an early stage (E12-E15) of submandibular salivary gland (SMG) development inhibits end bud...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (9): 1950–1960.
Published: 01 May 2014
.... Published by The Company of Biologists Ltd 2014 Apicobasal polarity Epithelial organ development Salivary gland Tubulogenesis Drosophila Epithelial tissues in multicellular organisms are manifested by apicobasal polarity, which is essential for their correct form and function ( Laprise...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (10): 2160–2171.
Published: 15 May 2013
... known regarding how Fkh regulates tissue-specific gene expression. Here, we characterize Sage, a bHLH transcription factor expressed exclusively in the Drosophila salivary gland (SG). We show that Sage is required for late SG survival and normal tube morphology. We find that many Sage targets...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (9): 1981–1993.
Published: 01 May 2013
.... elegans GON-1, is required for cell migration during embryogenesis. AdamTS-A is expressed in multiple migratory cell types, including hemocytes, caudal visceral mesoderm (CVM), the visceral branch of the trachea (VBs) and the secretory portion of the salivary gland (SG). Loss of AdamTS-A causes defects in...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (16): 3040–3050.
Published: 15 August 2012
..., we generated genetic models of the sole Drosophila melanogaster PI4KII gene. A specific requirement for PI4KII emerged in larval salivary glands. In PI4KII mutants, mucin-containing glue granules failed to reach normal size, with glue protein aberrantly accumulating in enlarged Rab7-positive late...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (2): 411–422.
Published: 15 January 2012
... gland. The mouse E13 submandibular salivary gland epithelium consists of epithelial buds with a single layer of organized outer columnar cells (OCCs) surrounding a less organized cluster of central, or inner, polymorphic cells (IPCs) ( Kadoya and Yamashina, 2010 ; Walker et al., 2008 ). When cultured...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (1): 191–202.
Published: 01 January 2012
... ) Competing interests statement The authors declare no competing financial interests. 18 10 2011 © 2012. miR-200c Vldlr Salivary gland Mouse MicroRNAs (miRNAs) are small non-coding RNAs that target multiple messenger RNAs (mRNAs) and function as post-transcriptional...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (24): 5415–5427.
Published: 15 December 2011
...Na Xu; Gaiana Bagumian; Michael Galiano; Monn Monn Myat Generation and maintenance of proper lumen size is important for tubular organ function. We report on a novel role for the Drosophila Rho1 GTPase in control of salivary gland lumen size through regulation of cell rearrangement, apical domain...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (13): 2681–2691.
Published: 01 July 2011
...Otso Häärä; Sayumi Fujimori; Ruth Schmidt-Ullrich; Christine Hartmann; Irma Thesleff; Marja L. Mikkola The developing submandibular salivary gland (SMG) is a well-studied model for tissue interactions and branching morphogenesis. Its development shares similar features with other ectodermal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (24): 4177–4189.
Published: 15 December 2010
...Carolyn Pirraglia; Jenna Walters; Monn Monn Myat Generating and maintaining proper lumen size and shape in tubular organs is essential for organ function. Here, we demonstrate a novel role for p21-activated kinase 1 (Pak1) in defining the size and shape of the Drosophila embryonic salivary gland...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (16): 2935–2945.
Published: 15 August 2007
... Salivary gland Cleft formation Class 3 semaphorin Plexin Neuropilin (Npn1; Nrp1) Mouse Branching morphogenesis is a unique cellular process commonly observed during embryonic organogenesis. Examples of this process during development include the establishments of the airways of the lung, the...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (11): 2017–2025.
Published: 01 June 2007
...Katherine E. Harris; Steven K. Beckendorf Guided cell migration is necessary for the proper function and development of many tissues, one of which is the Drosophila embryonic salivary gland. Here we show that two distinct Wnt signaling pathways regulate salivary gland migration. Early in migration...
Journal Articles
Journal: Development
Development (2006) 133 (23): 4737–4748.
Published: 01 December 2006
... required for the maturation of the ducts of the salivary gland and kidney. In the mouse, Cp2l1 is specifically expressed in the developing ducts of a number of exocrine glands, including the salivary gland, as well as in those of the kidney. In Cp2l1 -deficient mice, the expression of genes directly...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (18): 3517–3527.
Published: 15 September 2006
...Elliott W. Abrams; Whitney K. Mihoulides; Deborah J. Andrew (Fkh) is required to block salivary gland apoptosis, internalize salivary gland precursors, prevent expression of duct genes in secretory cells and maintain expression of CrebA , which is required for elevated secretory function. Here, we...
Journal Articles
Journal: Development
Development (2005) 132 (12): 2743–2758.
Published: 15 June 2005
... in the Drosophila salivary gland. We show that expression of genes encoding proteins required for ER targeting and translocation, and proteins that mediate transport between the ER and Golgi is very high in the early salivary gland. This high level expression requires two early salivary gland...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (10): 2317–2327.
Published: 15 May 2004
..., although linked to cell cycle control mechanisms,are regulated by dMyc and dMnt. A Delta Vision microscope (Applied Precision) was used to take 0.2-0.5μm sections through nuclei in the posterior salivary gland or fat body. The fluorescent intensity of single nuclei was calculated using the ImageQuant...