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Keywords: Salamander
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Journal Articles

Activation of Smad2 but not Smad3 is required to mediate TGF-β signaling during axolotl limb regeneration

Jean-François Denis, Fadi Sader, Samuel Gatien, Éric Villiard, Anie Philip, Stéphane Roy
Journal: Development
Development (2016) 143 (19): 3481–3490.
https://doi.org/10.1242/dev.131466
Published: 1 October 2016
... signaling has been implicated in scar formation after wounding. During axolotl limb regeneration, differential regulation of Smad effectors may explain why these animals do not scar. Axolotl Epimorphic Regeneration TGF-β signaling Smad2 Smad3 Limb Salamander Urodeles A mbystoma mexicanum...
View article titled, Activation of Smad2 but not Smad3 is required to mediate TGF-β signaling during axolotl limb regeneration
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Includes: Supplementary data
Journal Articles

Neuregulin-1 signaling is essential for nerve-dependent axolotl limb regeneration

Johanna E. Farkas, Polina D. Freitas, Donald M. Bryant, Jessica L. Whited, James R. Monaghan
Journal: Development
Development (2016) 143 (15): 2724–2731.
https://doi.org/10.1242/dev.133363
Published: 1 August 2016
.... The neuronally secreted protein Neuregulin-1 is required for regeneration, and can induce it in denervated limbs. ErbB2 Neuregulin-1 Axolotl Regeneration Salamander Northeastern University; Howard Hughes Medical Institute National Science Foundation...
View article titled, Neuregulin-1 signaling is essential for nerve-dependent axolotl limb regeneration
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Includes: Supplementary data
Journal Articles

Efficient regeneration by activation of neurogenesis in homeostatically quiescent regions of the adult vertebrate brain

Daniel A. Berg, Matthew Kirkham, Anna Beljajeva, Dunja Knapp, Bianca Habermann, Jesper Ryge, Elly M. Tanaka, András Simon
Journal: Development
Development (2010) 137 (24): 4127–4134.
https://doi.org/10.1242/dev.055541
Published: 15 December 2010
...Daniel A. Berg; Matthew Kirkham; Anna Beljajeva; Dunja Knapp; Bianca Habermann; Jesper Ryge; Elly M. Tanaka; András Simon In contrast to mammals, salamanders and teleost fishes can efficiently repair the adult brain. It has been hypothesised that constitutively active neurogenic niches...
View article titled, Efficient regeneration by activation of neurogenesis in homeostatically quiescent regions of the adult vertebrate brain
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Includes: Supplementary data