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Keywords: STAT1
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Journal Articles
Journal: Development
Development (2005) 132 (15): 3345–3356.
Published: 1 August 2005
... of Dnmt1 deficiency on GFAP gene expression is restricted to the gliogenic NPCs that give rise to more GFAP-positive astrocytes. Astroglial differentiation is regulated by LIF-induced activation of the JAK-STAT pathway. The major STAT proteins expressed in the nervous system are STAT1 and STAT3...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2001) 128 (11): 2119–2129.
Published: 1 June 2001
... proliferation and we have previously shown that the transcription factor STAT1 mediates the growth inhibitory effect of FGF in vitro. We provide genetic evidence that STAT1 is a modulator of the negative regulation of bone growth by FGF in vivo. We crossed Stat1 −/− mice with a transgenic mouse line...