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1-2 of 2
Keywords: STAT1
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Journal Articles
DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling
FreeGuoping Fan, Keri Martinowich, Mark H. Chin, Fei He, Shaun D. Fouse, Leah Hutnick, Daisuke Hattori, Weihong Ge, Yin Shen, Hao Wu, Johanna ten Hoeve, Ke Shuai, Yi E. Sun
Journal:
Development
Development (2005) 132 (15): 3345–3356.
Published: 1 August 2005
... during the neuro- to gliogenic switch in the developing CNS. To further examine the relationship between changes in DNA methylation and gliogenesis, we analyzed the methylation status of the mouse Gfap,Stat1 and S100β genes in neurogenic and gliogenic NPCs. Within the Gfap promoter, we focused...
Includes: Supplementary data
Journal Articles
STAT1 mediates the increased apoptosis and reduced chondrocyte proliferation in mice overexpressing FGF2
Available to Purchase
Journal:
Development
Development (2001) 128 (11): 2119–2129.
Published: 1 June 2001
... proliferation and we have previously shown that the transcription factor STAT1 mediates the growth inhibitory effect of FGF in vitro. We provide genetic evidence that STAT1 is a modulator of the negative regulation of bone growth by FGF in vivo. We crossed Stat1 −/− mice with a transgenic mouse line...