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Keywords: SRF
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Journal Articles
Journal Articles
Journal: Development
Development (2019) 146 (7): dev164129.
Published: 4 April 2019
...Ashley A. DeAguero; Lizzet Castillo; Sandy T. Oas; Kaveh Kiani; Anton L. Bryantsev; Richard M. Cripps ABSTRACT Serum response factor (SRF) has an established role in controlling actin homeostasis in mammalian cells, yet its role in non-vertebrate muscle development has remained enigmatic. Here, we...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (15): 2853–2861.
Published: 1 August 2016
... of MRTFs to the nucleus where they activate serum response factor (SRF), a regulator of actin and other cytoskeletal protein genes. SRF is an essential regulator of skeletal muscle differentiation and numerous components of the muscle sarcomere, but the potential involvement of MRTFs in skeletal muscle...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (11): 2321–2333.
Published: 1 June 2013
... sprouting is essential for embryonic, postnatal and tumor development. Serum response factor (SRF) is known to be important for embryonic vascular development. Here, we studied the effect of inducible endothelial-specific deletion of Srf in postnatal and adult mice. We find that endothelial SRF activity...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (4): 769–777.
Published: 15 February 2007
... the ectodermal territory and enhances the inducing activity of the Activin signal. SRF interacts with Smad2 and FAST-1, and inhibits the formation of the Smad2-FAST-1 complex induced by Activin. These results suggest that XSRF might act to ensure proper mesoderm induction in the appropriate region by inhibiting...
Journal Articles
Journal: Development
Development (1998) 125 (19): 3801–3808.
Published: 1 October 1998
...Ricardo Escalante; Leandro Sastre ABSTRACT A homolog of the Serum Response Factor (SRF) has been isolated from Dictyostelium discoideum and its function studied by analyzing the consequences of its gene disruption. The MADS-box region of Dictyostelium SRF (DdSRF) is highly conserved with those...
Journal Articles
Journal: Development
Development (1989) 107 (4): 835–846.
Published: 1 December 1989
... 1 Present address: National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK 25 09 1989 © 1989 by Company of Biologists 1989 c-fos oncogenes development gene expression Xenopus SRF Fertilisation of the amphibian egg triggers...