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Keywords: SREBP2
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Journal Articles
Shuyi Mai, Xiaoxuan Zhu, Esther Yi Ching Wan, Shengyu Wu, Jesslyn Nagalin Yonathan, Jun Wang, Ying Li, Jessica Yuen Wuen Ma, Bing Zuo, Dennis Yan-yin Tse, Pui-Chi Lo, Xin Wang, Kui Ming Chan, David M. Wu, Wenjun Xiong
Journal:
Development
Development (2022) 149 (14): dev200633.
Published: 14 July 2022
... mechanisms of eye size control remain poorly understood. Here, we discovered that the lipogenic transcription factor sterol regulatory element-binding protein 2 (SREBP2) has an unanticipated function in the retinal pigment epithelium (RPE) to promote eye size in postnatal mice. SREBP2 transcriptionally...
Includes: Supplementary data
