1-8 of 8
Keywords: SMO
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development (2013) 140 (1): 56–65.
Published: 1 January 2013
..., its receptor Patched (Ptc), a 12-pass transmembrane protein, inhibits the activation of Smoothened (Smo), a seven-pass transmembrane protein required for Hh signal transduction ( Fig. 1C , ‘OFF’) ( Alcedo et al., 1996 ; Chen and Struhl, 1996 ; van den Heuvel and Ingham, 1996 ). With Smo inhibited...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (19): 4219–4231.
Published: 1 October 2011
...Qing Shi; Shuang Li; Jianhang Jia; Jin Jiang Hedgehog (Hh) transduces signal by regulating the subcellular localization and conformational state of the GPCR-like protein Smoothened (Smo) but how Smo relays the signal to cytoplasmic signaling components remains poorly understood. Here, we show...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (9): 1423–1432.
Published: 1 May 2009
... ) 19 2 2009 © 2009. 2009 Hedgehog SMO Ductal morphogenesis Hyperplasia Pituitary isograft Tissue interaction Mouse Mammary gland development requires both systemic hormones and local growth factor-mediated tissue interactions. Classical hormone ablation/replacement...
Journal Articles
Journal: Development
Development (2009) 136 (8): 1387–1396.
Published: 15 April 2009
... or other essential components of the Shh signaling pathway. Using Cre/ loxP -mediated tissue-specific inactivation of the smoothened ( Smo ) gene in the developing palatal mesenchyme, we show that the epithelially expressed Shh signals directly to the palatal mesenchyme to regulate palatal mesenchyme cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (2): 307–316.
Published: 15 January 2009
...Hongge Jia; Yajuan Liu; Wei Yan; Jianhang Jia The seven-transmembrane protein Smoothened (Smo) and Zn-finger transcription factor Ci/Gli are crucial components in Hedgehog (Hh) signal transduction that mediates a variety of processes in animal development. In Drosophila , multiple kinases have been...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (6): 1309–1318.
Published: 15 March 2004
... have genetically manipulated smoothened ( Smo ), which encodes a transmembrane protein that is essential for transducing all Hedgehog (Hh) signals. Removal of Smo from perichondrial cells by the Cre-LoxP approach prevents formation of a normal bone collar and also abolishes development of the primary...
Journal Articles
Journal Articles