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1-2 of 2
Keywords: Rspo1
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Journal Articles
In collection:
Stem cells & regeneration
Journal:
Development
Development (2017) 144 (4): 590–600.
Published: 15 February 2017
..., processes regulated by Notch and Wnt. We hypothesized that coordination of HSC specification with vessel patterning might involve modulatory regulatory factors such as R-spondin 1 (Rspo1), an extracellular protein that enhances β-catenin-dependent Wnt signaling and has previously been shown to regulate ISV...
Includes: Supplementary data
Journal Articles
Anne-Amandine Chassot, Stephen T. Bradford, Aurélie Auguste, Elodie P. Gregoire, Eric Pailhoux, Dirk G. de Rooij, Andreas Schedl, Marie-Christine Chaboissier
Journal:
Development
Development (2012) 139 (23): 4461–4472.
Published: 1 December 2012
... is activated by the expression of the Y-linked gene Sry , which promotes cell proliferation and differentiation of Sertoli cells, the supporting cells of the testis. In absence of Sry (XX individuals), activation of WNT/CTNNB1 signalling, via the upregulation of Rspo1 and Wnt4 , promotes ovarian...
Includes: Supplementary data