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Keywords: Ribosome biogenesis
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Neural development
Journal: Development
Development (2019) 146 (10): dev173765.
Published: 28 May 2019
... exhibited NTDs resembling those seen in Lin28a/b dKO mice. Increased NPC numbers and brain sizes in Lin28a-overexpressing mice were rescued by Rpl24 Bst/+ heterozygosity. Mechanistically, polysome profiling revealed reduced translation of genes involved in the regulation of cell cycle, ribosome biogenesis...
Includes: Supplementary data
Journal Articles