... of two neurons that is established through signaling pathways from adjacent neurons that are functionally different. Drosophila Eye Opsin Rhodopsin Japan Society for the Promotion of Science http://dx.doi.org/10.13039/501100001691 JP15029244 Okayama University...

... combinatorial transcription factor input, feedback and redundancy, are coordinated to drive dve expression in the Drosophila eye. Defective proventriculus Shadow enhancer Dark shadow enhancer Rhodopsin Drosophila retina Photoreceptor Spineless Orthodenticle Spalt Genes are expressed...

... of light-detecting Rhodopsin proteins. In one R8 subtype, active Hippo signaling induces Rhodopsin 6 (Rh6) and represses Rhodopsin 5 (Rh5), whereas in the other subtype, inactive Hippo signaling induces Rh5 and represses Rh6. The activity state of the Hippo pathway in R8 cells is determined...

... synthesized membrane proteins at the trans -Golgi network (TGN). To identify which genes are essential for these sorting mechanisms, we screened mutants in which the transport of Rhodopsin 1 (Rh1), an apical integral membrane protein in Drosophila photoreceptors, was affected. We found that deficiencies...

.... Transcriptional profiling revealed that Pph13 plays an integral role in promoting rhabdomeric photoreceptor cell function. Pph13 regulates Rh2 and Rh6 , and other phototransduction genes, demonstrating that Pph13 and Otd control a distinct subset of Rhodopsin-encoding genes in adult visual systems. Bioinformatic...

[email protected]) * These authors contributed equally to this work † Present address: Department of Molecular Biology and Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA Competing interests statement 2 6 2010 © 2010. Rhodopsin...

...Akiko K. Satoh; Joseph E. O'Tousa; Koichi Ozaki; Donald F. Ready In developing Drosophila photoreceptors, rhodopsin is trafficked to the rhabdomere, a specialized domain within the apical membrane surface. Rab11, a small GTPase implicated in membrane traffic, immunolocalizes to the trans-Golgi...

..., morphology or chirality. * Author for correspondence (e-mail: [email protected]) 18 12 2001 26 02 2001 © 2001 by Company of Biologists 2001 Drosophila eye Ommatidia Rhodopsin Planar polarity Genetic screen In the past decade, Drosophila has proven...

... and default cell-fates in the R8 cell. * Author for correspondence (e-mail: [email protected]) 16 03 1999 04 05 1999 © 1999 by Company of Biologists 1999 Retina Drosophila melanogaster Photoreceptor Cell- fate determination Rhodopsin Opsin Cell patterning One...

... projection targets in the brain (for review see Hardie, 1985). All cells of the primary system, R1-R6, express the same rhodopsin and are functionally identical. In contrast, the R7 and R8 photoreceptors are different from each other. They occupy anatomically precise positions, with R7 on top of R8. In fact...

...Justin P. Kumar; Donald F. Ready ABSTRACT Null mutations of the Drosophila Rh1 rhodopsin gene, ninaE , result in developmental defects in the photosensitive membranes, the rhabdomeres, of compound eye photoreceptors R1-R6. In normal flies, Rh1 expression begins at about 78% of pupal life...