... generation at apical, lateral or basal sides of epithelial Drosophila wing disc cells, an important model for studying morphogenesis. We show that optogenetic recruitment of RhoGEF2 to apical, lateral or basal cell sides leads to local accumulation of F-actin and increase in mechanical tension. Increased...

.... These effects also are mediated through coordinated effects on myosin activity and adhesion, suggesting a common mechanism for Diaphanous action during morphogenesis. * Author for correspondence (e-mail: [email protected] ) 10 1 2008 © 2008. 2008 Myosin Formins RhoGEF2 Drosophila...

...-mail: [email protected] ) 24 8 2005 ©2005. 2005 Cadherin Morphogenesis RhoGEF2 Shotgun During animal development, coordinated changes in cell shape and position build the body plan and drive morphogenesis. These changes are executed in part by the actin cytoskeleton, and neighboring...