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Keywords: RhoGEF
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Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2021) 148 (11): dev199232.
Published: 14 June 2021
... of the ventral furrow. Actomyosin Morphogenesis RhoGAP RhoGEF Tissue folding Transcriptional patterning Drosophila National Institutes of General Medical Sciences R01GM125646 Alexander von Humboldt-Stiftung Massachusetts Institute of Technology http://dx.doi.org...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (24): dev168922.
Published: 12 December 2018
... is not shared by arhgef3 , which encodes another organizer-specific RhoGEF. Plekhg5 protein is localized in the apical cell cortex via its pleckstrin homology domain, and the GEF activity enhances its apical recruitment. Plekhg5 induces apical actomyosin accumulation and cell elongation. Knockdown of plekhg5...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (24): 4937–4946.
Published: 15 December 2013
... discovered a new mechanism for regulating the Wnt pathway: activity of a Rho guanine nucleotide exchange factor (GEF) encoded by pebble ( pbl ) in Drosophila and ECT2 in humans. This RhoGEF has an essential role in cytokinesis, but also plays an unexpected, conserved role in inhibiting Wg/Wnt activity. Loss...
Journal Articles
Journal Articles
Journal: Development
Development (2005) 132 (18): 4165–4178.
Published: 15 September 2005
... gastrulation, the Drok embryos have more severe cellularization defects than RhoGEF2 and some of these defects (particularly those involving nuclear morphology and fall-out) may even precede cellularization. This result is consistent with the idea that the RhoGEFs involved in activating Rho signaling tend...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2004) 131 (11): 2641–2651.
Published: 1 June 2004
... to their neighbours and extend very few protrusions. Consistent with the dependence of the mesoderm EMT and cytokinesis on actin organisation, the GTP exchange function of the PBL RhoGEF is required for both processes. By contrast, the N-terminal BRCT domains of PBL are required only for the cytokinetic function...
Journal Articles
Journal: Development
Development (2002) 129 (5): 1215–1223.
Published: 1 March 2002
...-squash Rho RhoGEF Morphogenesis Drosophila melanogaster © 2002. 2002 12 12 2001 *Author for correspondence (e-mail: nishida@bio.nagoya-u.ac.jp ) ...