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Keywords: Retinal development
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Journal Articles
Journal: Development
Development (2021) 148 (12): dev199399.
Published: 18 June 2021
...Michael L. Kaufman; Noah B. Goodson; Ko Uoon Park; Michael Schwanke; Emma Office; Sophia R. Schneider; Joy Abraham; Austin Hensley; Kenneth L. Jones; Joseph A. Brzezinski ABSTRACT During retinal development, a large subset of progenitors upregulates the transcription factor Otx2 , which is required...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2019) 146 (17): dev178103.
Published: 9 September 2019
.... Together, these data represent a valuable resource shedding light on transcription factor sequences and guidance cue dynamics during mouse retinal development. Seminal work using vector lineage tracing identified fundamental aspects of the logic that allows various retinal cell fates ( Turner and Cepko...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (8): 1368–1381.
Published: 15 April 2017
... as a ‘gold standard’ can help ensure that RPE products are functionally authentic ( Miyagishima et al., 2016 ). The substantial body of knowledge regarding retinal development in vivo , which has been acquired largely from animal models, can be used to guide efforts to produce human retinal cells...
Journal Articles
Journal: Development
Development (2016) 143 (21): 3895–3906.
Published: 1 November 2016
... signals play a role in setting up DV polarity in mouse ESC-derived optic cups. Morphogenesis Organoid culture Pattern formation Retinal development Vertebrate eye development is a complex event that requires rigorous polarity regulation with specific gene expression patterns...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2016) 143 (12): 2172–2182.
Published: 15 June 2016
... proteins. Fig. 6. Fat3 and Ena/VASP proteins are enriched in the IPL throughout retinal development. (A) Western blot analysis confirmed the presence of Mena, VASP and EVL in retinal lysates from E17.5 to P11, which spans amacrine cell development. Actin loading controls are shown underneath each...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (9): 1571–1584.
Published: 1 May 2016
...Andrea Barabino; Vicky Plamondon; Mohamed Abdouh; Wassim Chatoo; Anthony Flamier; Roy Hanna; Shufeng Zhou; Noboru Motoyama; Marc Hébert; Joëlle Lavoie; Gilbert Bernier ABSTRACT Retinal development occurs through the sequential but overlapping generation of six types of neuronal cells and one glial...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (4): 743–752.
Published: 15 February 2015
... development, a complete eye is formed but is subsequently lost. In Astyanax mexicanus , another blind cavefish, eye loss has been attributed to interference during eye field patterning. To address whether similar pathways have been targeted by evolution independently, we investigated the retinal development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (24): 4959–4969.
Published: 15 December 2013
... by The Company of Biologists Ltd 2013 Cell fate Eye Gsk3β Mitf Optic vesicle patterning Optic cup Retinal development Smad Vsx2 During vertebrate eye development, the optic neuroepithelium is specified into three domains: retinal pigment epithelium (RPE), neural retina (NR...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (1): 176–184.
Published: 1 January 2013
... and neuronal morphogenesis during embryonic and retinal development. Here we show that Abl is required for photoreceptor cell fate maintenance, as Abl mutant photoreceptors lose neuronal markers during late pupal stages but do not re-enter a proliferative state or undergo apoptosis. Failure to maintain...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (22): 4111–4121.
Published: 15 November 2012
... autonomous modes of organogenesis and homeostasis. We also attempt to interpret the results of previous in vivo studies of retinal development in light of the self-organising nature of the retina. * Author for correspondence ( yoshikisasai@cdb.riken.jp ) Competing interests statement The authors...
Journal Articles
Journal: Development
Development (2010) 137 (14): 2307–2317.
Published: 15 July 2010
... interests. 4 5 2010 © 2010. 2010 Neurogenesis Retinal development Transcription regulation Medaka The vertebrate retina is a layered structure composed of six neuronal and one glial cell type, which are organised in three cellular layers: the ganglion cell layer, comprising...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (11): 1981–1990.
Published: 1 June 2008
.... * Author for correspondence (e-mail: lin_gan@urmc.rochester.edu ) 31 3 2008 © 2008. 2008 LIM-homeodomain POU domain MATH5 ATOH7 POU4F2 RGC Retinal development Transcription factor Owing to its easy accessibility and well-organized laminar structure, the retina has long...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (22): 4439–4450.
Published: 15 November 2006
... and Endocrinology, Juntendo University,2-1-1 Hongo, Bunkyo-Ku, Tokyo 113-8421, Japan 30 8 2006 © 2006. 2006 Retinal development Basic helix-loop-helix Amacrine cell Horizontal cell Ganglion cell Lineage tracing Ptf1a Foxn4 Progenitor Cell specification The vertebrate neural...
Journal Articles
Journal: Development
Development (2005) 132 (9): 2035–2045.
Published: 1 May 2005
...@uni-duesseldorf.de ) 21 2 2005 ©2005. 2005 Zonula adherens crumbs Notch RhoA (Rho1) Retinal development Morphogenesis during animal development involves not only the specification of particular cell fates and differentiation of specific cell types...
Journal Articles
Journal: Development
Development (2001) 128 (24): 5051–5060.
Published: 15 December 2001
... OVE1070 ( Fig. 2 A-C). Nevertheless, the dorsal RPE continues to develop as neural retina, indicating that sustained FGF9 stimulation is not necessary for retinal development. Further evidence that a transient signal is sufficient to switch the RPE differentiation pathway comes from the transgenic mice...