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Keywords: Repulsion
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Journal Articles
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Neural development
Journal: Development
Development (2016) 143 (12): 2183–2193.
Published: 15 June 2016
... trajectories in open-book preparations of Syk −/− ; Zap70 −/− mouse embryos, we show that Syk kinases are dispensable for attraction towards the midline but confer growth cone responsiveness to repulsive signals that expel commissural axons from the midline. Known to serve a repulsive function at the midline...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (12): 2473–2482.
Published: 15 June 2014
..., and rescue of eye vesicle integrity with simultaneous knockdown of sema6a and plxna2 , point to an eye-autonomous requirement for Sema6a/Plxna2. We propose a novel, tissue-autonomous mechanism of organ cohesion, with neutralization of repulsion suggested as a means to promote interactions between cells...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (9): 1940–1949.
Published: 1 May 2014
... at the site of dorsal root entry. Our results suggest that Sema5B contributes to a repulsive barrier for centrally projecting primary sensory axons, forcing them to turn and establish the dorsal funiculus. References Adams R. H. , Betz H. , Püschel A. W. ( 1996 ). A novel class...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (15): 2539–2550.
Published: 1 August 2010
... Competing interests statement 18 5 2010 © 2010. Branching Chick Fasciculation Mouse Neurite outgrowth Nogo-A Repulsion Developing neurons send out processes that reach their targets guided mostly by extracellular cues that are either permissive, attractive...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (14): 2417–2426.
Published: 15 July 2010
...Hope A. Coleman; Juan-Pablo Labrador; Rebecca K. Chance; Greg J. Bashaw Slits and their Roundabout (Robo) receptors mediate repulsive axon guidance at the Drosophila ventral midline and in the vertebrate spinal cord. Slit is cleaved to produce fragments with distinct signaling properties...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (20): 3475–3484.
Published: 15 October 2009
... influence these patterning and avoidance processes by promoting attractive, repulsive or adhesive responses to specific cues. The Drosophila transmembrane protein Turtle (Tutl) and its orthologs in other species are conserved members of the immunoglobulin superfamily, the in vivo functions of which...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (2): 273–284.
Published: 15 January 2007
...-Spectrin in midline repulsion. Surprisingly, neither the Ankyrin-binding nor the pleckstrin homology (PH) domains of β-Spectrin are required for accurate guidance decisions. α-Spectrin is dependent upon β-Spectrin for its normal subcellular localization and/or maintenance, whereas α- spectrin mutants...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (20): 4483–4495.
Published: 15 October 2005
.... 2005 Motoneurons Hindbrain Slit Robo Repulsion Rat Chick During development, axons are guided by contact-mediated and diffusible cues ( Mueller, 1999 ; Huber et al., 2003 ). In the developing vertebrate embryo hindbrain, the floor plate is the origin of such cues, repelling motor...
Journal Articles
Journal: Development
Development (2001) 128 (22): 4545–4552.
Published: 15 November 2001
... to regulate defasciculation. *Author for correspondence (e-mail: gctp@hamon.swmed.edu ) 22 8 2001 © 2001. 2001 Axon Guidance Beat Beaten Path Attraction Repulsion Drosophila Cell adhesion molecule The regulation of axon outgrowth during neuronal development...