... renal cell type underpinning the water-conservation mechanism of a major beetle lineage is derived from an ancestrally present cell type and specified by a conserved transcription factor repertoire. Tribolium Tiptop/Teashirt Dachshund Renal development Cryptonephridial complex...

... specific and lineage-independent effects in renal development. Although it has been proposed that activation of β-catenin within the nephron progenitors or renal vesicles leads to tumor formation through inhibition of MET or activation of EMT, respectively, our findings suggest that activation of this gene...

... appearance of PDGFRβ + VMCs play a crucial role in patterning the vascular and interstitial components of the developing kidney ( Fig. 7 ). Fig. 7. Model for Pbx1-dependent vascular patterning in the developing kidney. In wild-type (WT) kidney, during the initial stages of renal development, Pbx1...

... was investigated by deleting integrin β1 at initiation (E10.5) and late(E18.5) stages of development. Deletion at E10.5 resulted in a severe branching morphogenesis phenotype. Deletion at E18.5 did not alter renal development but predisposed the collecting system to severe injury following ureteric obstruction. β1...

..., RARαβ2 − mutants displayed small kidneys, containing few ureteric bud branches, reduced numbers of nephrons and lacking the nephrogenic zone where new nephrons are continuously added. These observations have prompted us to investigate the role of RARα and RARβ2 in renal development in detail. We have...

... by Company of Biologists 1993 neurotrophin receptors renal development phosphorothioate oligodeoxynucleotides Inductive cell-cell interactions are major forces for development of multicellular organisms. In a few cases, these interactions have been clarified at the molecular level...

... address: Department of Physiology and Biophysics, Cornell Medical College, New York, NY 10021, USA † Permanent address: National Institute of Cardiovascular Research, Osaka, Japan 26 11 1991 © 1992 by Company of Biologists 1992 metanephros lineage analysis stem cells renal...