... extravillous trophoblast cells identifies a conserved regulatory network governing the invasive trophoblast cell population. Trophoblast Rat Single nucleus Chromatin Placentation Regulatory networks Candidate TFs driving gene regulation in invasive trophoblast cells were identified through...

...) in the extracellular space. Bottom: representation of the signalling occurring from ectodermal/epidermal to mesenchymal cells. (B) Left: hypothetical gene regulatory network for skeletal cells built with data coming from this work and previous publications ( Dylus et al., 2016 , 2018 ; Czarkwiani et al., 2013...

... towards the AC. During this migration, this VPC is exposed to increasing concentrations of EGF that further promote the 1° fate. In summary, multiple levels of control confer robustness that cannot be described by a gradient model alone ( Hoyos et al., 2011 ). These regulatory networks also involve cell...

.... Long noncoding RNAs Regulatory networks Stem cell differentiation Israeli Centers for Research Excellence 10.13039/501100005386 1796/12 Israel Science Foundation 10.13039/501100003977 1242/14 1984/14 European Research Council 10.13039/501100000781...

...) wts-lacZ was lost in BEAF null mutant clones (GFP−) compared with control tissue (GFP+). (D) Model for BEAF regulation of wts and melt expression. Dashed lines represent clone boundary. To explore how BEAF regulates the R8 regulatory network, we examined five independent ChIP datasets (four...

... Transcription factors (TFs) act within wider regulatory networks to control cell identity and fate. Numerous TFs, including Scl (Tal1) and PU.1 (Spi1), are known regulators of developmental and adult haematopoiesis, but how they act within wider TF networks is still poorly understood. Transcription activator...

...Aurore L'Honoré; Jean-François Ouimette; Marisol Lavertu-Jolin; Jacques Drouin The MyoD gene is part of the core regulatory network that governs skeletal myogenesis and acts as an essential determinant of the myogenic cell fate. Although generic regulatory networks converging on this gene have been...