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Keywords: Regulatory network
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Journal Articles
Journal: Development
Development (2020) 147 (24): dev192948.
Published: 24 December 2020
... experiments validated the regulatory roles of miR-340-5p and Foxm1 in the Wnt-FoxO-Hippo subnetwork, as well as the role of miR-129-5p in the miR-129-5p– Col1a1 subnetwork. Thus, our study helps understand the comprehensive regulatory mechanisms for craniofacial development. The co-regulatory network...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (6): dev159830.
Published: 22 March 2018
..., and identify a novel composite T-box–Hox DNA motif that integrates Hox modulation of Tbx-dependent transcription. Limb specification Regulatory network ChIPseq Tbx4 Hoxc10 Pitx1 Tbx5 Hoxa13 Hoxd13 Tetrapod limbs develop under the control of a common genetic program that is conserved...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (18): 3325–3335.
Published: 15 September 2017
... expressed dataset, although accompanied by a few novel limb type-restricted genes, validates the results of our transcriptomic approach. With a thorough characterization of FL versus HL gene regulatory networks in hand, revealing extensive low-magnitude expression changes and very few limb type...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (4): 595–608.
Published: 15 February 2016
.... The motif recovered from the wild-type tumor data, GAAACCTGATCC, closely matches the TGAAACCTGA recovered from the SIX1/2 motif. A comparative analysis of tumor and developmental programs might identify regulatory networks and gene targets responsible for the persistence of these tumor cells through...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (3): 477–485.
Published: 1 February 2015
...., 2009 ). The mathematical model used here to explore the connection between cell cycle dynamics and Notch signaling in neural progenitors consists of a regulatory network that encompasses cell cycle regulators, the transcription factor Ngn2, the Notch effector Hes1 and the Delta-like Notch ligand Dll1...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (14): 3067–3078.
Published: 15 July 2011
... formation Transcription control Cis-regulatory element Regulatory network Long-range regulation Drosophila The Drosophila segmentation genes ( Nusslein-Volhard et al., 1987 ; Nusslein-Volhard and Wieschaus, 1980 ) form a hierarchical regulatory network consisting of the maternal, gap, pair...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (21): 4173–4181.
Published: 1 November 2006
...Paola Oliveri; Katherine D. Walton; Eric H. Davidson; David R. McClay The foxa gene is an integral component of the endoderm specification subcircuit of the endomesoderm gene regulatory network in the Strongylocentrotus purpuratus embryo. Its transcripts become confined to veg2, then veg1...
Journal Articles
Journal: Development
Development (2005) 132 (8): 1843–1854.
Published: 15 April 2005
..., which together with their spatial expression patterns leads to a model of the regulatory network specified by PAL-1. § Author for correspondence (e-mail: hunter@mcb.harvard.edu ) * Present address: Biology Division, California Institute of Technology,Pasadena, CA 91125, USA † Division...
Includes: Multimedia, Supplementary data