.... However, increasing evidence suggests that they could arise in a self-organizing manner. Here, we introduce the Sevilletor, a novel reaction-diffusion system that serves as a framework to compare different somitogenesis patterning hypotheses. Using this framework, we propose the Clock and Wavefront Self...

...Shigeru Kondo ABSTRACT The Turing model (or reaction-diffusion model), first published in 1952, is a mathematical model that can account for autonomy in the morphogenesis of organisms. Although initially controversial, the model has gradually gained wider acceptance among experimental embryologists...

...Andrew D. Economou; Nicholas A. M. Monk; Jeremy B. A. Green ABSTRACT Periodic patterning is widespread in development and can be modelled by reaction-diffusion (RD) processes. However, minimal two-component RD descriptions are vastly simpler than the multi-molecular events that actually occur...

... reveals that a two-step process underlies the observed self-organization and subsequent fate acquisition. Developmental organoids Human gastrulation Morphogenesis Pluripotent stem cells Positional information Reaction-diffusion During development, pluripotent stem cells (PSCs...

...Jeremy B. A. Green; James Sharpe One of the most fundamental questions in biology is that of biological pattern: how do the structures and shapes of organisms arise? Undoubtedly, the two most influential ideas in this area are those of Alan Turing's ‘reaction-diffusion’ and Lewis Wolpert's...

...Tom W. Hiscock; Sean G. Megason How periodic patterns are generated is an open question. A number of mechanisms have been proposed – most famously, Turing's reaction-diffusion model. However, many theoretical and experimental studies focus on the Turing mechanism while ignoring other possible...

... has led us to consider Turing’s (1952) reaction-diffusion theory and its relatives to explain the tip pattern. This class of theories can account for the rather precise spacing of tips, as well as for their simultaneous emergence from an initially unpatterned state ( Byrne & Cox, 1987...

... BLG 583 (ed. S. Bonotto , F. Cinelli & R. Billiau ), pp. 109 - 119 . Mol, Belgium: Belgian Nuclear Center. Harrison , L. G. & KolÄr , M. ( 1988 ). Coupling between reaction-diffusion prepattem and expressed morphogenesis, applied to desmids and dasyclads...