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Keywords: RdDM
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Journal Articles
Marta A. Mendes, Rosanna Petrella, Mara Cucinotta, Edoardo Vignati, Stefano Gatti, Sara C. Pinto, Dayton C. Bird, Veronica Gregis, Hugh Dickinson, Matthew R. Tucker, Lucia Colombo
Journal:
Development
Development (2020) 147 (23): dev194274.
Published: 13 December 2020
... in the premeiotic ovule. Previously, it was reported that mutants in the RNA-dependent DNA methylation (RdDM) pathway might be involved in restricting the female germline to a single nucellus cell. We show that the DRM methyltransferase double mutant drm1drm2 also presents ectopic enlarged cells, consistent...
Includes: Supplementary data
Journal Articles
Thiet Minh Vu, Miyuki Nakamura, Joseph P. Calarco, Daichi Susaki, Pei Qi Lim, Tetsu Kinoshita, Tetsuya Higashiyama, Robert A. Martienssen, Frédéric Berger
Journal:
Development
Development (2013) 140 (14): 2953–2960.
Published: 15 July 2013
.... However, genome-wide studies suggested other DNA methylation-dependent imprinting mechanisms. Here, we show that de novo RNA-directed DNA methylation (RdDM) regulates imprinting at specific loci expressed in endosperm. RdDM in somatic tissues is required to silence expression of the paternal allele...
Includes: Supplementary data