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Keywords: Rb
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Journal Articles
Journal: Development
Development (2006) 133 (14): 2695–2704.
Published: 15 July 2006
... caused by a null mutation in the tumor-suppressor and class B synMuv gene lin-35 Rb and a gain-of-function mutation in let-60 Ras are suppressed by reduction of isw-1 function,NURF complex proteins might be effective targets for cancer therapy. † Author for correspondence (e-mail: horvitz@mit.edu...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (17): 4299–4310.
Published: 1 September 2004
...Kathryn A. Wikenheiser-Brokamp pRb, p107 and p130 are important regulators of cell cycle and have extensive overlapping functions; however, only Rb has been shown to be a bone fide tumor suppressor. Defining the overlapping versus distinct pocket protein functions is therefore an important step...
Journal Articles
Journal Articles