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Keywords: Rat
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Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2020) 147 (4): dev183798.
Published: 21 February 2020
...-gastrulating embryos in mammals, and subsequently migrate towards gonads to mature into functional gametes. Here, we investigated PGC development in rats, by genetically modifying Prdm14 , a unique marker and an essential PGC transcriptional regulator. We trace PGC development in rats, for the first time, from...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (22): 4224–4235.
Published: 15 November 2016
... of GDNF and GFRα1 is required for proper development of hippocampal dendritic arbors and spine maturation through NCAM signaling. GDNF Dendrite complexity Dendritic spines Structural plasticity Hippocampus NCAM Mouse Rat The development of complex, type-specific dendrite morphology...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (9): 1560–1570.
Published: 01 May 2016
... induce death of sensory neurons in vitro . The extent to which Sema3A regulates developmental cell death in vivo , however, is debated. We show that in compartmentalized cultures of rat sympathetic neurons, a Sema3A-initiated apoptosis signal is retrogradely transported from axon terminals to cell bodies...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (2): 303–313.
Published: 15 January 2015
... experiments using postnatal or adult SVZ progenitors reveal key differences in the connective properties of the neurons generated. Adult neurogenesis Synaptic development Fate determination Subventricular zone Rat New neurons are continuously added to the adult mammalian brain. The most...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (21): 4087–4097.
Published: 01 November 2014
... by The Company of Biologists Ltd 2014 Hmga2 Self-renewal Retina Progenitors Epigenetic Stem cells Rat The vertebrate retina is a simple and accessible central nervous system (CNS) model, facilitating our understanding of how the brain develops and functions. It consists of seven different...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (21): 3986–3996.
Published: 01 November 2012
... plate. Taken together, these results suggest a biochemical and functional interaction between APP and pancortins, and reveal a previously unidentified role for pancortins in mammalian cortical development. Sprague Dawley rats (Charles River Laboratories, Wilmington, MA, USA) were housed and cared...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (20): 3775–3785.
Published: 15 October 2012
...@inserm.fr ) Competing interests statement The authors declare no competing financial interests. 26 7 2012 © 2012. Published by The Company of Biologists Ltd 2012 Polarity Traffic Actin Cochlea Van Gogh-like 2 Gipc1 Myosin VI Planar polarity Mouse Rat In epithelia...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (19): 3600–3612.
Published: 01 October 2012
... 2012. Cdh1-APC Smurf1 Axon growth Myelin Ubiquitylation Mouse Rat Axon growth is a crucial process in the developing nervous system. It is controlled by a large number of extrinsic regulatory events, which trigger signaling cascades that involve small GTPase-controlled...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (18): 3306–3315.
Published: 15 September 2012
... ) * These authors contributed equally to this work Competing interests statement The authors declare no competing financial interests. 18 6 2012 © 2012. Astrocyte fate Oligodendroglial differentiation Multiple sclerosis Regeneration Spinal cord injury Rat Cdkn1c...
Journal Articles
Journal: Development
Development (2011) 138 (19): 4301–4313.
Published: 01 October 2011
... RNA splicing and editing Two-photon calcium imaging Rat * Author for correspondence ( mohammad.hamad@rub.de ) Dendrites receive and integrate synaptic inputs, and during development dendritic trees grow under the control of neuronal activity. Studies have provided compelling...
Journal Articles
Journal: Development
Development (2011) 138 (2): 227–235.
Published: 15 January 2011
... a method for long-term videomicroscopy to follow the lineages of rat perinatal RPCs cultured at clonal density. In such cultures, cell-cell interactions between two different clones are eliminated and the extracellular environment is kept constant, allowing us to study the cell-intrinsic potential...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (14): 2279–2287.
Published: 15 July 2010
...Harry G. Leitch; Kate Blair; William Mansfield; Harold Ayetey; Peter Humphreys; Jennifer Nichols; M. Azim Surani; Austin Smith Mouse and rat embryonic stem cells can be sustained in defined medium by dual inhibition (2i) of the mitogen-activated protein kinase (Erk1/2) cascade and of glycogen...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (3): 415–426.
Published: 01 February 2009
... Autocrine Mouse Rat FAK (Ptk2) N-WASP (Wasl) To form a myelin sheath, an oligodendrocyte initially extends multiple branching processes that survey the local environment for suitable axons( Hardy and Friedrich, 1996 ; Kirby et al., 2006 ). Upon contact with a target axon, oligodendrocyte...
Journal Articles
Journal: Development
Development (2008) 135 (17): 2855–2864.
Published: 01 September 2008
..., suggesting that this might facilitate directing regenerating axons to appropriate targets. * Author for correspondence (e-mail: timothy.kennedy@mcgill.ca ) 28 6 2008 © 2008. 2008 Axon guidance DCC ROCK PRK C3 Y27632 Regeneration Growth cone Rho GTPases Rat During...
Journal Articles
Journal: Development
Development (2007) 134 (17): 3213–3225.
Published: 01 September 2007
... Rat Mesencephalic dopaminergic (mesDA) neurons play important roles in the control of movement and behavior, and degeneration or dysfunction of these neurons can lead to severe neurological disorders such as Parkinson's disease( Olanow and Tatton, 1999 ). Cell replacement therapy is one...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (9): 1723–1736.
Published: 01 May 2007
... Dystroglycan Oligodendrocyte Laminin Myelin Integrin DRG Rat Extrinsic regulatory molecules, such as growth factors, are important for oligodendrocyte development during central nervous system (CNS) myelination. Although less is known about the extrinsic regulation of oligodendrocyte development...
Journal Articles
Journal: Development
Development (2006) 133 (21): 4269–4279.
Published: 01 November 2006
... of cholangiocyte marker-positive fetal liver epithelial cells (CMP-FLEC). Differentiation potential was evaluated by injecting cell isolates from dipeptidyl peptidase IV (DPPIV) positive (DPPIV+) Fischer donor rats into the spleen of partially hepatectomized, DPPIV negative (DPPIV-)Fischer host rats exposed...
Journal Articles
Journal: Development
Development (2006) 133 (12): 2359–2369.
Published: 15 June 2006
...Yong Zhan; Akihiro Fujino; David T. MacLaughlin; Thomas F. Manganaro; Paul P. Szotek; Nelson A. Arango; Jose Teixeira; Patricia K. Donahoe Examination of Müllerian inhibiting substance (MIS) signaling in the rat in vivo and in vitro revealed novel developmental stage- and tissue-specific events...
Journal Articles
Journal: Development
Development (2006) 133 (10): 1923–1931.
Published: 15 May 2006
...-rabbit IgG antibody (Molecular Probes). To obtain cDNA fragments for Ecad, VEcad, Rcad, BRcad, Cad8, Cad11,Mcad and Cad6 , we performed PCR using cDNAs from E15 rat brains or E14 whole rat embryos as templates. Following primers were used: Ecad , (forward) 5′-ggagggttttcactggttgttgg-3...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (8): 1543–1551.
Published: 15 April 2006
... for correspondence (e-mail: erguen@uke.uni-hamburg.de ) * These authors equally contributed to this work 8 2 2006 © 2006. 2006 Rat Vasculogenesis VEGFR Angiogenesis is defined as outgrowth of new vessels from pre-existing blood vessels ( Carmeliet, 2003 ; Folkman, 2003...
Includes: Supplementary data