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Keywords: Rapamycin
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Journal Articles
Journal: Development
Development (2020) 147 (21): dev184291.
Published: 20 April 2020
... is impaired in mice that lack osteoclasts. Last, we show that rapamycin can suppress the growth of bone lymphatics in our models of GLA and GSD. In summary, we show that bLECs can arise from pre-existing LECs and that rapamycin can prevent the growth of bone lymphatics. * Author for correspondence...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (2): dev177840.
Published: 23 January 2020
... , whereas lowering autophagy efficiency in the non-aging Hydra vulgaris induces an aging phenotype. Aging model system Autophagy sensor Epithelial stem cells Hydra regeneration Evolution of aging p62/SQSTM1 WIPI2 Rapamycin National Institutes of Health 10.13039/100000002...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (7): dev172460.
Published: 8 April 2019
... not abolish, embryonic and adult myogenesis. Raptor Rictor Protein synthesis Satellite cells Muscle regeneration Rapamycin Canton of Basel-Stadt Canton of Basel-Landschaft Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 10.13039...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (16): 3343–3356.
Published: 15 August 2011
...Ryan C. Russell; Chong Fang; Kun-Liang Guan The mammalian target of rapamycin (mTOR) is a kinase that responds to a myriad of signals, ranging from nutrient availability and energy status, to cellular stressors, oxygen sensors and growth factors. The finely tuned response of mTOR to these stimuli...