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Keywords: Raf
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Journal: Development
Development (2018) 145 (11): dev163915.
Published: 6 June 2018
... expression is regulated differently between these two lineages. In the B5.1 lineage, Snail was activated through Tbx6.b , which is activated by maternal factors, including Zic-r.a. In the B6.4 lineage, the MAPK pathway was cell-autonomously activated by a constitutively active form of Raf, enabling Zic-r.a...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (10): 1765–1776.
Published: 15 May 2012
... in larval glial cells. Fifteen kinases were tested and silencing of two of them, Raf and Cdk12, resulted in a clear shift of Nrx-IV exon3 to Nrx-IV exon4 splicing ( Fig. 6B , supplementary material Table S1 ). nrxIV_2.0c1930a2_rev::atgccaattgtccatgTgttggtcgtggcaacg nrxIV_2.0c1930a2_for...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2001) 128 (7): 1183–1191.
Published: 1 April 2001
...Lihui Yang; Nicholas E. Baker ABSTRACT The Drosophila EGF receptor is required for differentiation of many cell types during eye development. We have used mosaic analysis with definitive null mutations to analyze the effects of complete absence of EGFR, Ras or Raf proteins during eye development...
Journal Articles
Journal Articles
Journal: Development
Development (1998) 125 (24): 4999–5008.
Published: 15 December 1998
...Willis Li; Michael Melnick; Norbert Perrimon ABSTRACT The small guanine nucleotide binding protein p21 Ras plays an important role in the activation of the Raf kinase. However, the precise mechanism by which Raf is activated remains unclear. It has been proposed that the sole function of p21 Ras...
Journal Articles
Journal: Development
Development (1997) 124 (20): 4163–4171.
Published: 15 October 1997
...Willis Li; Efthimios M. C. Skoulakis; Ronald L. Davis; Norbert Perrimon ABSTRACT 14-3-3 proteins have been shown to interact with Raf-1 and cause its activation when overexpressed. However, their precise role in Raf-1 activation is still enigmatic, as they are ubiquitously present in cells...
Journal Articles
Journal: Development
Development (1994) 120 (3): 569–578.
Published: 1 March 1994
...Fernando J. Diaz-Benjumea; Ernst Hafen ABSTRACT In Drosophila , Drk, an SH2 adaptor protein, Sos, a putative activator of Ras1, Ras1, raf and rolled/MAP kinase have been shown to be required for signalling from the sevenless and the torso receptor tyrosine kinase. From these studies, it was unclear...