1-1 of 1
Keywords: Rab8a
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche

Soumyashree Das, Shiyan Yu, Ryotaro Sakamori, Pavan Vedula, Qiang Feng, Juan Flores, Andrew Hoffman, Jiang Fu, Ewa Stypulkowski, Alexis Rodriguez, Radek Dobrowolski, Akihiro Harada, Wei Hsu, Edward M. Bonder, Michael P. Verzi, Nan Gao
Journal: Development
Development (2015) 142 (12): 2147–2162.
https://doi.org/10.1242/dev.121046
Published: 15 June 2015
... the homeostasis of adult tissues. Wnt signaling is a crucial regulator of the stem cell niche, but the mechanism that governs Wnt ligand delivery in this compartment has not been fully investigated. We identified that Wnt secretion is partly dependent on Rab8a-mediated anterograde transport of Gpr177 (wntless...
View articletitled, Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche
Open the PDF for Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche in another window
Includes: Supplementary data