.... Biol. Cell 15 , 4990 - 5000 . 10.1091/mbc.e04-04-0355 Pelissier , A. , Chauvin , J.-P. and Lecuit , T. ( 2003 ). Trafficking through Rab11 endosomes is required for cellularization during Drosophila embryogenesis . Curr. Biol. 13 , 1848 - 1857 . 10.1016/j.cub...

...Jaeho Yoon; Jerlin Garo; Moonsup Lee; Jian Sun; Yoo-Seok Hwang; Ira O. Daar ABSTRACT Rab11 family-interacting protein 5 (Rab11fip5) is an adaptor protein that binds to the small GTPase Rab11, which has an important function in endosome recycling and trafficking of cellular proteins to the plasma...

..., although the precise mechanism remains inconclusive. Here, we report that, in zebrafish, the Crumbs complex component MPP5a interacts with small GTPase Rab11 in Golgi to transport cadherin and Crumbs components synergistically to the apical domain, thus establishing apical epithelial polarity and adherens...

... kinase (Rock), regulate apical constriction of bottle cells at the blastopore and ectopic constriction of ectoderm cells triggered by the actin-binding protein Shroom3. At the blastopore lip, Vangl2 is required for the apical accumulation of the recycling endosome marker Rab11. We also show that Rab11...

.../VEGF receptor (PVR) is required for a polarized distribution of recycling endosome and exocyst in the leading cells of the border cell cluster. Interestingly, PVR signaled through the small GTPase Rac to positively affect the levels of Rab11-labeled recycling endosomes, probably in an F-actin-dependent...

... of the pericentriolar accumulation of Rab11-positive endosomes, through which the Notch ligand, Delta is recycled. Our work characterizes an additional mode of asymmetric centrosome movement during asymmetric divisions and suggests a model whereby the asymmetry in centrosome movements participates in differential Notch...

... propose that Vangl2 and cofilin cooperate to target Rab11 + vesicles containing PCP proteins to the apical membrane during the initiation of planar cell polarity. ‡ Author for correspondence ( [email protected] ) * Present address: Department of Pediatrics, Yale School of Medicine...

... to promote growth. We have identified an essential role for the bristle cuticle in the maintenance of bristle structure and shape at late stages of bristle development. We show that the small GTPase Rab11 mediates the organized deposition of chitin, a major cuticle component in bristles, and disrupting Rab11...

... statement The authors declare no competing financial interests. 22 12 2011 © 2012. Zebrafish Muscle specific kinase MuSK Unplugged Wnt11 Dishevelled Rab11 Recycling endosome Neuromuscular junction Planar cell polarity AChR pre-pattern Motor axons...

.... Thus, subcellular localization of Wingless along the apical-basal axis of receiving cells may be instrumental in shaping the Wingless gradient. * Author for correspondence (e-mail: [email protected] ) 3 11 2005 © 2006. 2006 Rab5 Rab7 Rab11 Imaginal disc Polarized endocytosis...

...Akiko K. Satoh; Joseph E. O'Tousa; Koichi Ozaki; Donald F. Ready In developing Drosophila photoreceptors, rhodopsin is trafficked to the rhabdomere, a specialized domain within the apical membrane surface. Rab11, a small GTPase implicated in membrane traffic, immunolocalizes to the trans-Golgi...

... of the microtubule cytoskeleton. We present evidence that the Drosophila oocyte also contains important asymmetries in its membrane trafficking pathways. Specifically, we show that α-adaptin and Rab11, which function critically in the endocytic pathways of all previously examined animal cells, are localized...