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Keywords: RYK
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Journal Articles
Journal: Development
Development (2020) 147 (20): dev195388.
Published: 27 October 2020
... return to the basal side. WNT5A, which is secreted by surrounding mesenchymal cells, acts as a guidance cue to orchestrate this epithelial pathfinding behavior, but how this signal is received by epithelial cells is unknown. Here, we have investigated two known WNT5A receptors: ROR2 and RYK. We found...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (3): 409–419.
Published: 01 February 2011
... factors regulate cell-fate changes, are poorly understood. We have discovered that the Wnt receptor Ryk promotes GABAergic neuron production while repressing oligodendrocyte formation in the ventral telencephalon. We demonstrate that Ryk controls the cell-fate switch by negatively regulating expression of...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (13): 2277–2287.
Published: 01 July 2008
...Rene R. Wouda; Monique R. K. S. Bansraj; Anja W. M. de Jong; Jasprina N. Noordermeer; Lee G. Fradkin Members of the RYK/Derailed family have recently been shown to regulate axon guidance in both Drosophila and mammals by acting as Wnt receptors. Little is known about how the kinase activity...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (11): 2017–2025.
Published: 01 June 2007
... WNT5 WNT4 RYK Migration Salivary gland Wnt signaling plays a crucial role in many developmental processes,including cell fate determination, cell proliferation and cell migration. Many of these processes are carried out through the Frizzled family of receptors. Of the four Drosophila...