... , 2815 - 2822 . 10.1242/dev.128.14.2815 Johnstone , O. and Lasko , P. ( 2001 ). Translational regulation and RNA localization in Drosophila oocytes and embryos . Annu. Rev. Genet. 35 , 365 - 406 . 10.1146/annurev.genet.35.102401.090756 Jurczyk , A. , Gromley...

... 2021 © 2021. Published by The Company of Biologists Ltd 2021 Summary: Use of proximity biotin ligation to identify components of a Dynein localization complex and the development of a nanobody-based approach to identify the interactome of any GFP-tagged protein. RNA localization...

.../ Summary: An shRNA depletion strategy has uncovered the role of Dlc in the dimerization of Egl, further revealing a step-wise assembly pathway for building a localization-competent mRNP. RNA localization Molecular motor Kinesin Cell polarity Cargo adaptor Drosophila National...

... of inscuteable mRNAs in neuroblasts ( Hughes et al., 2004 ). Clathrin heavy chain Drosophila oogenesis RNA localization Germ line Microtubules Polarity formation © 2014. Published by The Company of Biologists Ltd 2014 25 5 2013 4 3 2014 Competing interests The authors...

... localization during animal development. * Authors for correspondence ( [email protected] ; [email protected] ) Competing interests statement The authors declare no competing financial interests. © 2012. RNA localization RNA transport Local translation Cell polarity Post...

... RNA and, particularly, the sqt 3′UTR, leads to ectopic nuclear β-catenin accumulation and expands dorsal gene expression. Dorsal activity of sqt RNA requires Wnt/β-catenin but not Oep-dependent Nodal signaling. Unexpectedly, sqt ATG morpholinos block both sqt RNA localization and translation...

... Johnston D. , Brand A. H. ( 1998 ). Miranda mediates asymmetric protein and RNA localization in the developing nervous system . Genes Dev. 12 , 1847 - 1857 . Shulman J. M. , Benton R. , St Johnston D. ( 2000 ). The Drosophila homolog of C. elegans PAR-1 organizes...

... Building, University of Alberta, Edmonton,Alberta, Canada 27 9 2007 © 2008. 2008 wingless RNA localization RNA structure Apical localization element Stem-loop The subcellular localization of a mRNA controls the site of protein translation, thereby enriching the protein...

... for correspondence (e-mail: [email protected] ) 19 8 2005 ©2005. 2005 Ascidian embryo Halocynthia roretzi RNA localization postplasmic/PEM RNA Cortical endoplasmic reticulum Germ plasm POPK-1 kinase Sad-1 kinase mRNA localization occurs in a diversity of organisms...

...-LE contains 16 copies of the previously defined CAC-containing signal motifs for RNA localization. A critical number of such repeats seems to be required for accumulation in the mitochondrial cloud along the early pathway, but additional repeats seem to be required for localization along the late...

...Young J. Yoon; Kimberly L. Mowry RNA localization is a key mechanism for generating cell and developmental polarity in a wide variety of organisms. We have performed studies to investigate a role for the Xenopus homolog of the double-stranded RNA-binding protein, Staufen, in RNA localization during...

.../bioclip.html 6 8 2003 © 2003. 2003 Ascidian embryo Maternal mRNA Egg cortex RNA localization Endoplasmic reticulum † Author for correspondence (e-mail: [email protected] ) * These authors contributed equally to this work Localization of specific mRNAs is essential...

... ) 18 9 2002 ©2002. 2002 FUSE-binding protein KSRP Prrp RNA localization Vg1 mRNA VgRBP71 ZBP2 Xenopus The strict temporal and spatial localization of maternal mRNA underlies the asymmetric development of oocytes and embryos( Kloc et al., 2002 ; Lipshitz and Smibert, 2000...

... and Orb bind competitively to oskar mRNA with opposite effects on translation and RNA localization. *Author for correspondence (e-mail: [email protected] ) 5 10 2001 © 2002. 2002 yps Oogenesis RNA localization Translation Drosophila melanogaster Y-box protein...

... that regions around the ‘crescent’ structure contain endoplasmic reticulum (ER) (M. K. and L. D. E., unpublished observations). The involvement of the ER in RNA localization has been suggested in previous studies ( Deshler et al., 1997 ). Our identification of the ‘crescent’ structure may add a new component...

... that localization of nanos RNA by components of the posteriorly localized germ plasm activates its translation by preventing interaction of nanos RNA with translational repressors. This mutually exclusive relationship between translational repression and RNA localization is mediated by a 180 nucleotide region...

... 1998 01 04 1998 © 1998 by Company of Biologists 1998 Drosophila RNA localization axis patterning vasa ( vas ) oogenesis Segregation of the germline from the soma is a central feature of animal development. In Drosophila , the germline is determined through...

... localization. We suggest that the Vg1 localization element is composed of smaller, redundant sequence motifs and identify one such 6-nt motif as essential for localization. These results allow insight into what constitutes an RNA localization signal and how RNA sequence elements may act in the localization...

... axis formation RNA localization Egfr signalling asymmetry maelstrom gurken Anterior/posterior (A/P) and dorsal/ventral (D/V) polarity in the Drosophila oocyte is established through a series of inductive interactions between the oocyte and the adjacent monolayer of somatic follicle...

... cytoskeleton axis formation RNA localization Bicaudal-D ( Bic-D ) egg chamber follicle cell nurse cell Asymmetric localization of patterning factors within cells often underlies developmental patterning, and Drosophila oogenesis has proven to be a valuable system for studying how...