... that germ cell specification mechanisms are conserved between mice and crickets. Inductive signaling Primordial germ cell PGC Blimp1 Prdm1 Gryllus bimaculatus RNA interference The cells that make up multicellular organisms can be divided into two major categories based...

... Delta Notch Segmentation Growth zone RNA interference Segmental organization of the anterior-posterior (AP) body axis is observed in diverse animal phyla, including arthropods, annelids and chordates. However, there has been debate regarding whether segmentation among phyla has...

... expression during early development. To distinguish between a functional role for the transcript and properties inherent to transcription of long ncRNAs, we employed RNA interference-based technology to deplete Kcnq1ot1 transcripts. We hypothesized that post-transcriptional depletion of Kcnq1ot1 ncRNA would...

... Regeneration Neurogenesis Neuronal progenitors Interstitial stem cells RNA interference ParaHox gene β-Tubulin Hydra belongs to Cnidaria, a phylum that arose before bilaterians and provides model systems to trace back ancestral developmental processes, as such as apical and anterior patterning...

...-dependent gene expression in termite workers. Our approach involved RNA interference (RNAi), bioassays and quantification of gene expression. We first investigated the expression of 17 morphogenesis-associated genes in response to RNAi-based hexamerin silencing. Hexamerin silencing resulted in significant...

... brachyenteron caudal Posterior patterning RNA interference Molecular mechanisms of anteroposterior (AP) patterning and segmentation are best understood in Drosophila melanogaster , and this knowledge provides a basis for investigating the evolution of these processes in the phylum Arthropoda...

... for correspondence (e-mail: [email protected] ) 30 3 2006 © 2006. 2006 MIS MIS type I/II receptor SMAD Epithelial-to-mesenchymal transition RNA interference Organ culture Rat Müllerian inhibiting substance (MIS; also known as anti-Müllerian hormone...

... and imaginal discs. Here, we test the signalling properties of these molecules in the embryonic epidermis. We demonstrate that RNA interference silencing of dally-like , but not dally , gives a segment polarity phenotype identical to that of null mutations in wingless or hedgehog. Using heterologous expression...

...Petr Svoboda; Paula Stein; Harutoshi Hayashi; Richard M. Schultz ABSTRACT Specific mRNA degradation mediated by double-stranded RNA (dsRNA), which is termed RNA interference (RNAi), is a useful tool with which to study gene function in several systems. We report here that in mouse oocytes, RNAi...