...Elizabeth R. Westbrook; Hugh Z. Ford; Vlatka Antolović; Jonathan R. Chubb ABSTRACT The distribution of mRNA in tissue is determined by the balance between transcription and decay. Understanding the control of RNA decay during development has been somewhat neglected compared with transcriptional...

...Jennifer N. Chousal; Abhishek Sohni; Kristoffer Vitting-Seerup; Kyucheol Cho; Matthew Kim; Kun Tan; Bo Porse; Miles F. Wilkinson; Heidi Cook-Andersen ABSTRACT Nonsense-mediated RNA decay (NMD) is a highly conserved RNA turnover pathway that degrades RNAs harboring in-frame stop codons in specific...

... controlled at different levels, including RNA decay. N 6 -methyladenosine (m6A) methylation-mediated degradation of RNA is essential for brain development. However, m6A methylation impacts not only RNA stability, but also other RNA metabolism processes. How RNA decay contributes to brain development...