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Keywords: RGC
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Journal Articles
Journal: Development
Development (2022) 149 (8): dev199694.
Published: 26 October 2021
...Si Chen; Kira L. Lathrop; Takaaki Kuwajima; Jeffrey M. Gross ABSTRACT Visual information is transmitted from the eye to the brain along the optic nerve, a structure composed of retinal ganglion cell (RGC) axons. The optic nerve is highly vulnerable to damage in neurodegenerative diseases...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (16): dev176586.
Published: 21 August 2019
...Maurício Rocha-Martins; Beatriz C. de Toledo; Pedro L. Santos-França; Viviane M. Oliveira-Valença; Carlos H. Vieira-Vieira; Gabriel E. Matos-Rodrigues; Rafael Linden; Caren Norden; Rodrigo A. P. Martins; Mariana S. Silveira ABSTRACT Retinal ganglion cell (RGC) degeneration is a hallmark of glaucoma...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (13): dev178012.
Published: 4 July 2019
...Pooja Teotia; Matthew J. Van Hook; Dietmar Fischer; Iqbal Ahmad ABSTRACT The poor axon regeneration in the central nervous system (CNS) often leads to permanent functional deficit following disease or injury. For example, degeneration of retinal ganglion cell (RGC) axons in glaucoma leads...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (11): 1981–1990.
Published: 1 June 2008
...-expressed with BRN3B, a POU-HD factor, in nascent post-mitotic retinal ganglion cells (RGCs). Similar to the Brn3b -null retinas, retina-specific deletion of Isl1 results in the apoptosis of a majority of RGCs and in RGC axon guidance defects. The Isl1 and Brn3b double null mice display more severe retinal...
Includes: Supplementary data