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Keywords: R-spondins
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Journal Articles
Journal: Development
Development (2014) 141 (15): 2959–2971.
Published: 1 August 2014
... second heart field (SHF) development. Here, we have examined the specific requirements for Nkx2-5 in the SHF progenitors. We show that Nkx2-5 potentiates Wnt signaling by regulating the expression of the R-spondin3 ( Rspo3 ) gene during cardiogenesis. R-spondins are secreted factors and potent Wnt...
Includes: Supplementary data