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Keywords: Purkinje fiber
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Journal Articles

Visualization and functional characterization of the developing murine cardiac conduction system

Stacey Rentschler, Dhananjay M. Vaidya, Houman Tamaddon, Karl Degenhardt, David Sassoon, Gregory E. Morley, José Jalife, Glenn I. Fishman
Journal: Development
Development (2001) 128 (10): 1785–1792.
https://doi.org/10.1242/dev.128.10.1785
Published: 15 May 2001
... 26 02 2001 19 04 2001 © 2001 by Company of Biologists 2001 Heart development Conduction system Purkinje fiber Mouse Optical mapping The rhythmic excitation of the mature heart depends upon the integrated function of the heterogeneous network of cells that together...
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Journal Articles

In vivo induction of cardiac Purkinje fiber differentiation by coexpression of preproendothelin-1 and endothelin converting enzyme-1

Kimiko Takebayashi-Suzuki, Masashi Yanagisawa, Robert G. Gourdie, Nobuyuki Kanzawa, Takashi Mikawa
Journal: Development
Development (2000) 127 (16): 3523–3532.
https://doi.org/10.1242/dev.127.16.3523
Published: 15 August 2000
... myocytes to endothelin-1 (ET-1), an endothelial cell-associated paracrine factor. These results suggest that an endothelial cell-derived signal is capable of inducing juxtaposed myocytes to differentiate into Purkinje fibers. It remains unexplained how Purkinje fiber recruitment is restricted...
View article titled, In vivo induction of cardiac <span class="search-highlight">Purkinje</span> <span class="search-highlight">fiber</span> differentiation by coexpression of preproendothelin-1 and endothelin converting enzyme-1
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Journal Articles

Terminal diversification of the myocyte lineage generates Purkinje fibers of the cardiac conduction system

Robert G. Gourdie, Tatsuo Mima, Robert P. Thompson, Takashi Mikawa
Journal: Development
Development (1995) 121 (5): 1423–1431.
https://doi.org/10.1242/dev.121.5.1423
Published: 1 May 1995
... of the central conduction system (e.g. atrioventricular ring and bundles). In quantitative analyses, we found that whereas the number of β-gal + myocyte nuclei per clone more than doubled between E14 and E18, the number of β-gal + Purkinje fiber nuclei remained constant. These data provide evidence that: (1...
View article titled, Terminal diversification of the myocyte lineage generates <span class="search-highlight">Purkinje</span> <span class="search-highlight">fibers</span> of the cardiac conduction system
Open the PDF for Terminal diversification of the myocyte lineage generates <span class="search-highlight">Purkinje</span> <span class="search-highlight">fibers</span> of the cardiac conduction system in another window