...Kazuto Fujishima; Junko Kurisu; Midori Yamada; Mineko Kengaku ABSTRACT The mechanism underlying the geometrical patterning of axon and dendrite wiring remains elusive, despite its crucial importance in the formation of functional neural circuits. The cerebellar Purkinje cell (PC) arborizes...

...Baiping Wang; Wilbur Harrison; Paul A. Overbeek; Hui Zheng Correct development of the cerebellum requires coordinated sonic hedgehog (Shh) signaling from Purkinje to granule cells. How Shh expression is regulated in Purkinje cells is poorly understood. Using a novel tyrosinase minigene-tagged...

... of the Lurcher cell death progression in tPA-deficient mice. Elimination of tPA delayed the apoptotic death of Purkinje and granule neurons in Lurcher mice, and reduced the phosphorylation of Jun and the activation of caspase 8. These results indicate that not only does tPA-promoted excitotoxic cell death...

... of the cerebellar cortex in the rat. I. The external germinal layer and the transitional molecular layer . J. Comp. Neurol . 145 , 353 – 97 . 10.1002/cne.901450305 Altman , J. ( 1972c ). Postnatal development of the cerebellar cortex in the rat. II. Phases in the maturation of Purkinje cells...