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Keywords: Pupariation
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Journal Articles

IP 3 R-mediated Ca 2+ release regulates protein metabolism in Drosophila neuroendocrine cells: implications for development under nutrient stress

Megha, Gaiti Hasan
Journal: Development
Development (2017) 144 (8): 1484–1489.
https://doi.org/10.1242/dev.145235
Published: 15 April 2017
... circuits, we investigated NE cell function during development under nutrient stress. Starved Drosophila larvae exhibited reduced pupariation if either insulin signaling or IP 3 /Ca 2+ signaling were downregulated in NE cells. Moreover, an IP 3 R (inositol 1,4,5-trisphosphate receptor) loss-of-function...
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Includes: Supplementary data