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Keywords: Ptf1a
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Journal Articles
Journal Articles
Journal: Development
Development (2019) 146 (13): dev164913.
Published: 27 June 2019
... systems, Dre/RoxP and Cre/LoxP, to independently trace green fluorescent Pdx1-lineage cells and red fluorescent Ptf1a-lineage cells in the developing and adult mouse pancreas. We detected a few Pdx1 + /Ptf1a − lineage cells in addition to the vast majority of Pdx1 + /Ptf1a + lineage cells in the pancreas...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (22): 4385–4394.
Published: 15 November 2014
... of a presumed pancreatic-commitment transcription factor, Ptf1a, in embryonic mouse endoderm (Ptf1a EDD ) dramatically expanded the pancreatic gene regulatory network within the foregut. Ptf1a EDD temporarily suppressed Sox2 broadly over the anterior endoderm. Pancreas-proximal organ territories underwent full...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (21): 4031–4041.
Published: 1 November 2014
... ). Consistent with this dynamic definition of the rhombic lip as an inductive interface, the lineage boundaries between the ventricular zone, rhombic lip and roof plate are somewhat blurred ( Fig. 5 ). The ventricular zone of the cerebellum is characterised by Ptf1a expression ( Fig. 5 A,B) and gives rise...
Journal Articles
Journal: Development
Development (2014) 141 (14): 2803–2812.
Published: 15 July 2014
...-helix transcription factors (TFs), Ascl1 and Ptf1a, have contrasting functions in specifying these neurons. To understand how Ascl1 and Ptf1a function in this process, we identified their direct transcriptional targets genome-wide in the embryonic mouse neural tube using ChIP-Seq and RNA-Seq. We show...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (10): 1744–1753.
Published: 15 May 2012
... expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue . Genes Dev. 20 , 1441 – 1446 . Apelqvist A. , Li H. , Sommer L. , Beatus P. , Anderson D. J. , Honjo T. , de Angelis M. H...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (1): 33–45.
Published: 1 January 2012
... and thereby represses Neurog3 and endocrine differentiation in neighboring cells by lateral inhibition. Here we show in mouse that Dll1 and Hes1 expression deviate during regionalization of early endoderm, and later during early pancreas morphogenesis. At that time, Ptf1a activates Dll1 in multipotent...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (22): 4011–4021.
Published: 15 November 2007
... exocrine tissue. * Author for correspondence (e-mail: isabelle.manfroid@ulg.ac.be ) 22 8 2007 © 2007. 2007 Zebrafish Pancreas FGF Signaling Endoderm Mesoderm ptf1a In amniotes, the pancreas originates from the thickening of the endodermal epithelium leading...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles