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Keywords: Prothoracic gland
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Journal Articles
Journal: Development
Development (2023) 150 (21): dev202024.
Published: 6 November 2023
...-independent mechanisms that remain less understood. To gain fundamental insights into the transcriptional activities of KDM5 proteins, we examined the essential roles of the single Drosophila Kdm5 ortholog during development. KDM5 performs crucial functions in the larval neuroendocrine prothoracic gland...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (22): dev190066.
Published: 27 November 2020
...Orathai Kamsoi; Xavier Belles ABSTRACT Insect metamorphosis originated around the middle Devonian, associated with the innovation of the final molt; this occurs after histolysis of the prothoracic gland (PG; which produces the molting hormone) in the first days of adulthood. We previously...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2014) 141 (20): 3955–3965.
Published: 15 October 2014
.... E. , Walkiewicz , M. and Stern , M. ( 2005 ). Ras activity in the Drosophila prothoracic gland regulates body size and developmental rate via ecdysone release . Curr. Biol. 15 , 1785 - 1795 . 10.1016/j.cub.2005.09.011 Carney , G. E. , Wade , A. A. , Sapra , R...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (23): 4730–4739.
Published: 1 December 2013
... coordinate growth and timing of maturation during development, the mechanisms generating these pulses are not known. Here we show that the ecdysone steroid pulse that drives the juvenile-adult transition in Drosophila is determined by feedback circuits in the prothoracic gland (PG), the major steroid...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (13): 2693–2703.
Published: 1 July 2011
...Ying Y. Gibbens; James T. Warren; Lawrence I. Gilbert; Michael B. O'Connor In insects, initiation of metamorphosis requires a surge in the production of the steroid hormone 20-hydroxyecdysone from the prothoracic gland, the primary endocrine organ of juvenile larvae. Here, we show that blocking...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2006) 133 (13): 2565–2574.
Published: 1 July 2006
... in the prothoracic gland (PG) and plays a central role in the control of development. Although many studies have revealed the biochemical features of ecdysone synthesis in the PG, many aspects of this pathway have remained unclear at the molecular level. We describe the neverland ( nvd ) gene, which encodes...
Includes: Supplementary data