... of the developing medulla to the lamina precursor, and it progresses in a single cell row width, which is called the proneural wave ( Fig. 1 ; Yasugi et al., 2008 ; Sato et al., 2013 ). As the current location of the proneural wave can be visualized by the expression of Lethal of Scute (L'sc), which is one...

... in a row of cells from medial to the lateral regions of the optic lobe, sweeping across the entire neuroepithelial sheet; it is preceded by the transient expression of the proneural gene lethal of scute [ l(1)sc ] and is thus called the proneural wave. We found that the epidermal growth factor receptor...

... neurons project their axons directly to corresponding lamina or medulla neurons. Here, we show that expression of the proneural protein Lethal of scute [L(1)sc] signals the transition of NE cells to NBs in the OOA. L(1)sc expression is transient, progressing in a synchronized and ordered `proneural wave...