.... , Sugie , A. , Umetsu , D. and Tabata , T. ( 2010 ). Coordinated sequential action of EGFR and Notch signaling pathways regulates proneural wave progression in the Drosophila optic lobe . Development 137 , 3193 - 3203 . 10.1242/dev.048058 Yasugi , T. , Fischer...

... in a row of cells from medial to the lateral regions of the optic lobe, sweeping across the entire neuroepithelial sheet; it is preceded by the transient expression of the proneural gene lethal of scute [ l(1)sc ] and is thus called the proneural wave. We found that the epidermal growth factor receptor...

... neurons project their axons directly to corresponding lamina or medulla neurons. Here, we show that expression of the proneural protein Lethal of scute [L(1)sc] signals the transition of NE cells to NBs in the OOA. L(1)sc expression is transient, progressing in a synchronized and ordered `proneural wave...