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Keywords: Progenitor cells
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Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2021) 148 (24): dev199512.
Published: 20 December 2021
...-resident endothelial progenitor cells in endotoxin-induced lung injury . Am. J. Respir. Cell Mol. Biol. 53 , 500 - 512 . 10.1165/rcmb.2014-0185OC Kim , T. , Chen , I. R. , Lin , Y. , Wang , A. Y.-Y. , Yang , J. Y. H. and Yang , P. ( 2019 ). Impact of similarity...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (23): dev178855.
Published: 4 December 2019
... such as the esophagus. However, the molecular mechanisms regulating these progenitor activities in the esophagus remain to be elucidated. Here, we demonstrated that Yap is required for the proliferation of esophageal progenitor cells (EPCs) in the developing murine esophagus. We found that Yap deficiency reduces EPC...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2019) 146 (9): dev175810.
Published: 1 May 2019
.... Yap Branching morphogenesis Airway differentiation Progenitor cells Lung development Alveolar differentiation The generation of organs with complex three-dimensional (3D) tubular architecture and distinct functional compartments, such as the mammary gland, kidney and lung, requires...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2016) 143 (7): 1099–1107.
Published: 1 April 2016
..., has not yet been achieved for continuously growing adult tissues, but is essential if we wish to understand the architecture of adult organs. The retinas of lower vertebrates grow throughout life from retinal stem cells (RSCs) and retinal progenitor cells (RPCs) at the rim of the retina, called...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (18): 3239–3251.
Published: 15 September 2015
... to quantify the regenerative potential of human mammary cells. Mammary stem cell Primary human mammary epithelial cells Basal Luminal Progenitor cells Branching morphogenesis Organoid Regenerative potential CD10 Terminal ductal-lobular units Collagen gel The mammary gland (MG) develops...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (6): 1028–1042.
Published: 15 March 2015
... of expansion and proliferation. The mammary gland thus provides an excellent model for studying the ‘stem/progenitorcells that allow this repeated expansion and renewal. In this Review, we provide an overview of the different cell types that constitute the mammary gland, and discuss how these cell types...
Journal Articles
Journal: Development
Development (2015) 142 (2): 258–267.
Published: 15 January 2015
... for homeostasis and repair of the conducting airways. Little is known about how these progenitor cells expand and transition to differentiation to form the pseudostratified airway epithelium in the developing and adult lung. Here, we show by genetic and pharmacological approaches that endogenous activation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (7): 1589–1598.
Published: 1 April 2014
... ( http://creativecommons.org/licenses/by/3.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Clonal lineage CRE recombinase piggyBac transposase Multi-fluorescence Progenitor cells Fate mapping...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2013) 140 (4): 740–750.
Published: 15 February 2013
... expressed in early retinal progenitor cells and that Sox4 expression began around birth, when expression of Sox11 subsided. To analyze the roles of Sox11 and Sox4 in retinal development, we perturbed their expression patterns in retinal explant cultures. Overexpression of Sox11 and Sox4 in retinal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (18): 3921–3930.
Published: 15 September 2011
... of the trunk. The NMs are deposited by a migrating pLL primordium, which is organized into polarized rosettes (proto-NMs). During migration, mature proto-NMs are deposited from the trailing part of the primordium, while progenitor cells in the leading part give rise to new proto-NMs. Wnt signaling is active...
Includes: Multimedia, Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2011) 138 (7): 1395–1407.
Published: 1 April 2011
... progenitor cell identity at the expense of differentiated cell phenotypes, we test whether genetic activation of Notch could rescue the Eya1 −/− lung phenotype, which is characterized by loss of epithelial progenitors, increased epithelial differentiation but reduced branching. Indeed, genetic activation...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2009) 136 (22): 3741–3745.
Published: 15 November 2009
... ). Is there a single self-renewing Id2 + progenitor cell type during the pseudoglandular stage? Or, are there separate bronchiolar and alveolar progenitors? To distinguish between these possibilities, we identified a dose of tmx that labeled either a single tip epithelial cell, or no cells, per lung. We exposed...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (1): 127–136.
Published: 1 January 2007
... Progenitor cells Forebrain Diencephalon ZLI Prethalamus Thalamus Pretectum Zinc finger The vertebrate forebrain is a tremendously complex structure and carries out essential functions such as regulating emotions, learning and memory, and hormonal homeostasis. It arises from anterior...
Includes: Supplementary data