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Keywords: Progenitor cell
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Journal Articles
Journal: Development
Development (2020) 147 (12): dev178582.
Published: 22 June 2020
... arise from a common thymic epithelial progenitor cell (TEPC). However, the mechanisms controlling cTEC and mTEC production from the common TEPC are not understood. Here, we show that emergence of the earliest mTEC lineage-restricted progenitors requires active NOTCH signaling in progenitor TEC and that...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (9): dev176974.
Published: 08 May 2019
... Biologists Ltd 2019 Summary: Research reported at the seventh EMBO meeting on the Molecular and Cellular Basis of Regeneration and Tissue Repair included important discoveries on regeneration and provided perspectives for regenerative medicine. Cell plasticity Progenitor cell Regeneration...
Journal Articles
Journal: Development
Development (2018) 145 (24): dev165381.
Published: 18 December 2018
.... The embryonic enthesis originates from Scx + / Sox9 + progenitor cells ( Blitz et al., 2013 ; Sugimoto et al., 2013 ). Yet, the contribution of these progenitors to the postnatal enthesis and their relation to the Gli1 lineage cells have never been studied. To fill this gap, we first examined...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (10): dev160184.
Published: 17 May 2018
... tissue homeostasis and disease, knowledge of the organ-specific origins of lymphatic endothelial progenitor cells remains limited. The assumption that most murine embryonic lymphatic endothelial cells (LECs) are venous derived has recently been challenged. Here, we show that the embryonic dermal blood...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (2): 211–220.
Published: 15 January 2017
... + progenitor cells in the endbuds of reconstituted glands. Addition of exogenous endothelial cells to reconstituted glands restored epithelial patterning, as did supplementation with the endothelial cell-regulated mesenchymal factors IGFBP2 and IGFBP3. Our results demonstrate that endothelial cells promote...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (10): 1831–1839.
Published: 15 May 2015
... superficially embedded within the quadriceps tendon. At the cellular level, we show that, similar to bone eminences, the patella is formed secondarily by a distinct pool of Sox9 - and Scx -positive progenitor cells. Finally, we show that TGFβ signaling is necessary for the specification of patella progenitors...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (1): 117–125.
Published: 01 January 2013
... Company of Biologists Ltd PTP1B (Ptpn1) Stat5 Mammary gland Stem cell Progenitor cell Mouse The epithelium of rodent and human mammary glands is hierarchically organized, encompassing cells at various differentiation stages ( Stingl et al., 2006b ; LaBarge et al., 2007...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (13): 2187–2197.
Published: 01 July 2009
... taste papillae. FST limits expansion and differentiation of Sox2 -expressing taste progenitor cells and negatively regulates the development of taste papillae in the lingual epithelium: in Fst -/- tongue, there is both ectopic development of Sox2 -expressing taste progenitors and accelerated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (13): 2289–2299.
Published: 01 July 2008
...Michael J. McGrew; Adrian Sherman; Simon G. Lillico; Fiona M. Ellard; Pippa A. Radcliffe; Hazel J. Gilhooley; Kyriacos A. Mitrophanous; Noemí Cambray; Valerie Wilson; Helen Sang The outgrowth of the vertebrate tail is thought to involve the proliferation of regionalised stem/progenitor cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (1): 145–157.
Published: 01 January 2008
...,there seems to be a reciprocal distribution of EGFP+ astrocytes and oligodendrocytes derived from Emx1-expressing cortical progenitor cells( Kessaris et al., 2006 ). The astrogliogenic potential of NG2 glia may depend on their site of origin. Alternatively, environmental factors in the dorsal forebrain...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (6): 1231–1242.
Published: 15 March 2007
...Ricardo C. Moraes; Xiaomei Zhang; Nikesha Harrington; Jennifer Y. Fung; Meng-Fen Wu; Susan G. Hilsenbeck; D. Craig Allred; Michael T. Lewis The hedgehog signaling network regulates pattern formation, proliferation,cell fate and stem/progenitor cell self-renewal in many organs. Altered hedgehog...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (15): 3027–3037.
Published: 01 August 2006
...Joanne G. W. Nijhof; Kristin M. Braun; Adam Giangreco; Carina van Pelt; Hiroshi Kawamoto; Richard L. Boyd; Rein Willemze; Leon H. F. Mullenders; Fiona M. Watt; Frank R. de Gruijl; Willem van Ewijk We describe a novel murine progenitor cell population localised to a previously uncharacterised region...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (14): 2639–2648.
Published: 15 July 2006
... persists into adulthood. Analysis of the expression of molecular markers, which characterize cell types in wild-type neural lineages,indicates that brat mutant clones comprise an excessive number of cells, which have molecular features of undifferentiated progenitor cells that lack nuclear Prospero (Pros...
Journal Articles
Journal: Development
Development (2005) 132 (2): 267–277.
Published: 15 January 2005
...Jérôme Teulière; Marisa M. Faraldo; Marie-Ange Deugnier; Michael Shtutman; Avri Ben-Ze'ev; Jean Paul Thiery; Marina A. Glukhova Wnt/β-catenin signaling pathway is involved in the maintenance of the progenitor cell population in the skin, intestine and other tissues, and its aberrant activation...
Journal Articles
Journal: Development
Development (2003) 130 (2): 391–399.
Published: 15 January 2003
... from the pool of proliferating progenitor cells and lead to a lasting effect of adult neurogenesis. * Author for correspondence (e-mail: gerd.kempermann@mdc-berlin.de ) 11 10 2002 © 2003. 2003 Stem cell Progenitor cell Adult neurogenesis Mouse In adult hippocampal...
Journal Articles
Journal: Development
Development (2002) 129 (16): 3873–3885.
Published: 15 August 2002
... self-renewing population of progenitor cells that are the primary source of cells driving the growth and morphogenesis of the myotome and dermomyotome in the epaxial domain of the body. *Author for correspondence (e-mail: ordahl@itsa.ucsf.edu ) 22 5 2002 © 2002. 2002 Myotome...