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Keywords: Primitive streak
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Journal Articles
Journal: Development
Development (2022) 149 (10): dev200295.
Published: 16 May 2022
... these. Using experimental manipulation of early chick embryos, including misexpression of an inducer (VG1 or ACTIVIN) and an inhibitor (BMP4), we test two alternative models for their ability to explain how the site of primitive streak formation is positioned relative to the rest of the embryo. In one model...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (4): dev180612.
Published: 16 February 2021
... and regenerative medicine. Axis elongation Gastrulation Neuromesodermal progenitors Primitive streak Tail bud Pluripotent stem cells Lineage specification in the early vertebrate embryo is initiated during gastrulation (see Glossary, Box 1 ), which involves the formation of the three germ...
Journal Articles
Journal Articles
Journal: Development
Development (2019) 146 (17): dev179564.
Published: 12 September 2019
...Iain Martyn; Eric D. Siggia; Ali H. Brivanlou ABSTRACT Although fate maps of early embryos exist for nearly all model organisms, a fate map of the gastrulating human embryo remains elusive. Here, we use human gastruloids to piece together a rudimentary fate map for the human primitive streak (PS...
Includes: Supplementary data
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Journal Articles
Journal: Development
Development (2013) 140 (13): 2691–2696.
Published: 1 July 2013
...Cantas Alev; Yuping Wu; Yukiko Nakaya; Guojun Sheng Mesoderm is formed during gastrulation. This process takes place at the blastopore in lower vertebrates and in the primitive streak (streak) in amniotes. The evolutionary relationship between the blastopore and the streak is unresolved...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (8): 1665–1675.
Published: 15 April 2013
...-dimensional body plan during gastrulation. In Tcf7l1 -/- embryos, specification of mesoderm is delayed, effectively uncoupling it from the induction of the primitive streak. Tcf7l1 repressor activity is necessary for a rapid switch in the response of pluripotent cells to Wnt/β-catenin stimulation, from one...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2010) 137 (17): 2863–2874.
Published: 1 September 2010
...Cantas Alev; Yuping Wu; Takeya Kasukawa; Lars M. Jakt; Hiroki R. Ueda; Guojun Sheng In birds and mammals, all mesoderm cells are generated from the primitive streak. Nascent mesoderm cells contain unique dorsoventral (D/V) identities according to their relative ingression position along the streak...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (4): 595–603.
Published: 15 February 2009
... a stepwise separation among its three main lineages, first between SMC progenitors and BC/EC common progenitors, and then between BCs and ECs. * Author for correspondence (e-mail: [email protected] ) 9 12 2008 © 2009. 2009 Chicken Chick Ventral mesoderm Primitive streak Smooth...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2007) 134 (15): 2829–2840.
Published: 1 August 2007
...Noemí Cambray; Valerie Wilson In mammals, the primitive streak region and its descendant, the tail bud,are the source of nascent mesoderm and spinal cord throughout axial elongation. A localised population of long-term axial progenitors has been identified in a region of the tail bud...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2006) 133 (19): 3767–3775.
Published: 1 October 2006
... in mesoderm development. Unlike Bmpr1a -null embryos, which fail to gastrulate, Bmpr-MORE embryos initiate gastrulation, but the recruitment of prospective paraxial mesoderm cells to the primitive streak is delayed. This delay causes a more proximal distribution of cells with paraxial mesoderm character...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (15): 2947–2959.
Published: 1 August 2006
... in sagittal section, was continuous with the embryonic primitive streak( Inman and Downs, 2006 ). Here,we have confirmed by transverse immunohistochemical sections that T lies within the allantoic core ( Fig. 1B , parts e-g). In the absence of T , only the outer few allantoic cell layers were maintained...
Journal Articles
Journal Articles
Journal: Development
Development (2002) 129 (15): 3609–3619.
Published: 1 August 2002
... cell system located in the primitive streak ( Nicolas et al., 1996 ; Stern et al., 1988 ; Selleck and Stern, 1991 ; Psychoyos and Stern, 1996 ). However, although this model accounts for the AP production of the myotome, and probably of the entire paraxial mesoderm, it does not address the issues...
Journal Articles