... is properly attributed. Summary: Initiation and termination of female germline stem cell differentiation requires the appearance and clearance of the same regulator, Bag of marbles. Germline RNA stability Post-transcriptional regulation Stem cells Drosophila Wellcome Trust http...

...-to-hematopoietic transition. HSPC generation is efficiently and accurately regulated by a variety of factors and signals; however, the precise control of these signals remains incompletely understood. Post-transcriptional regulation is crucial for gene expression, as the transcripts are usually bound by RNA...

... the identification of their roles in developmental mechanisms. Proteomics Post-transcriptional regulation Protein degradation Protein synthesis Paul G. Allen Frontiers Group Chan Zuckerberg Initiative CZF2019-002424 National Institutes of Health R01GM144967...

...Lisa Shao; Jaclyn M. Fingerhut; Brook L. Falk; Hong Han; Giovanna Maldonado; Yuemeng Qiao; Vincent Lee; Elizabeth Hall; Liang Chen; Gordon Polevoy; Greco Hernández; Paul Lasko; Julie A. Brill ABSTRACT Drosophila sperm development is characterized by extensive post-transcriptional regulation whereby...

... organization and microtubule-organizing center function. Here, we investigate the post-transcriptional regulation of Plp mRNA. We identify conserved binding sites for cytoplasmic polyadenylation element binding (CPEB) proteins within the Plp 3′-untranslated region and examine the role of the CPEB ortholog Oo18...

...Hui Li; Elizabeth R. Gavis ABSTRACT Dendritic arbor development is a complex, highly regulated process. Post-transcriptional regulation mediated by RNA-binding proteins plays an important role in neuronal dendrite morphogenesis by delivering on-site, on-demand protein synthesis. Here, we show how...

... defects in the gut, spiculogenesis and ciliogenesis. Sea urchin Primary mesenchyme cells miRNA target protector Post-transcriptional regulation Cilia National Institute of General Medical Sciences 10.13039/100000057 5P20GM103653-02 National Science Foundation 10.13039...

... localization and activity are mediated by sequences flanking the RNA-binding domain that bind specific molecular partners. Furthermore, these results identify a new role for DLC-1 in post-transcriptional regulation of gene expression. * Author for correspondence ( [email protected]...

... network is required for posterior crossvein (PCV) formation in the Drosophila pupal wing. Although both transcriptional and post-transcriptional regulation of co-factors in the network gives rise to tissue-specific and species-specific properties, their mechanisms are incompletely understood...

... that are distinct from those seen in Lfng loss-of-function embryos. Expression of clock-linked genes is perturbed and mature Hes7 transcripts are stabilized in the presomitic mesoderm of mutant mice, suggesting that both transcriptional and post-transcriptional regulation of clock components are perturbed by RLFNG...

... is a conserved, post-transcriptional regulator of muscle morphogenesis and structural gene expression. * Authors for correspondence ( [email protected] ; [email protected] ) Competing interests statement The authors declare no competing financial interests. 22 6 2013...

...-controlled post-transcriptional regulation of Bam is specific for male, but not for female, gametogenesis. Therefore, our data provide a new line of evidence showing distinct molecular mechanisms employed in male versus female germline stem cell differentiation pathways. However, the observation...

[email protected] ) Competing interests statement The authors declare no competing financial interests. 1 7 2012 © 2012. RNA-binding protein Post-transcriptional regulation Symmetric somitogenesis Left-right patterning Target protector morpholino Zebrafish...

...., unpublished), suggesting that a 5′ uracil also contributes to recognition by FBF. * Author for correspondence ( [email protected] ) Competing interests statement 6 4 2010 © 2010. Germ cells Meiosis Post-transcriptional regulation C. elegans A crucial step...

... regulating FGF signaling. * Author for correspondence (e-mail: [email protected] ). 28 4 2009 © 2009. 2009 FGF Mex3b RNA-binding protein Xenopus Neural plate Post-transcriptional regulation In developmental processes, embryonic induction and patterning...

... ) 28 7 2008 © 2008. 2008 Cytoskeleton Neurofilament Peripherin Post-transcriptional regulation Ribonucleoprotein Axonal outgrowth depends on coordinating the expression of functionally interrelated genes. For example, synthesis of cytoskeletal proteins and the associated...

... ) * These authors contributed equally to this work 14 2 2005 ©2005. 2005 Planarians Regeneration Neoblasts Stem cells RNAi Cell proliferation Pumilio PUF proteins Confocal microscopy TEM Cytofluorimetry In situ hybridization Post-transcriptional regulation Stem cells...

... being spliced out ( Fig. 6A,B ). We conclude that Myf5 primary transcripts are correctly spliced in neurons and the absence of Myf5 protein reflects subsequent stages of post-transcriptional regulation. Although the Myf5 protein is not accumulated in the embryonic mouse brain, the endogenous...

...′ untranslated region RNA stability Post-transcriptional regulation CAAC motif The fruit fly Drosophila melanogaster is covered with a regular and stereotyped array of external mechanosensory organs, which constitute the majority of its peripheral nervous system (PNS). The determination...