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Keywords: Positive selection
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Journal Articles

The pioneer transcription factors Foxa1 and Foxa2 regulate alternative RNA splicing during thymocyte positive selection

Ching-In Lau, Jasmine Rowell, Diana C. Yanez, Anisha Solanki, Susan Ross, Masahiro Ono, Tessa Crompton
Journal: Development
Development (2021) 148 (15): dev199754.
https://doi.org/10.1242/dev.199754
Published: 29 July 2021
...Ching-In Lau; Jasmine Rowell; Diana C. Yanez; Anisha Solanki; Susan Ross; Masahiro Ono; Tessa Crompton ABSTRACT During positive selection at the transition from CD4 + CD8 + double-positive (DP) to single-positive (SP) thymocyte, TCR signalling results in appropriate MHC restriction and signals...
View article titled, The pioneer transcription factors Foxa1 and Foxa2 regulate alternative RNA splicing during thymocyte <span class="search-highlight">positive</span> <span class="search-highlight">selection</span>
Open the PDF for The pioneer transcription factors Foxa1 and Foxa2 regulate alternative RNA splicing during thymocyte <span class="search-highlight">positive</span> <span class="search-highlight">selection</span> in another window
Includes: Supplementary data
Journal Articles

Gli3 in fetal thymic epithelial cells promotes thymocyte positive selection and differentiation by repression of Shh

Anisha Solanki, Diana C. Yanez, Susan Ross, Ching-In Lau, Eleftheria Papaioannou, Jiawei Li, José Ignacio Saldaña, Tessa Crompton
Journal: Development
Development (2018) 145 (3): dev146910.
https://doi.org/10.1242/dev.146910
Published: 31 January 2018
... thymic epithelial cells (TECs) promotes positive selection and differentiation from CD4 + CD8 + to CD4 + CD8 − single-positive (SP4) cells in the fetal thymus and that Gli3 represses Shh . Constitutive deletion of Gli3 , and conditional deletion of Gli3 from TECs, reduced differentiation to SP4, whereas...
View article titled, Gli3 in fetal thymic epithelial cells promotes thymocyte <span class="search-highlight">positive</span> <span class="search-highlight">selection</span> and differentiation by repression of Shh
Open the PDF for Gli3 in fetal thymic epithelial cells promotes thymocyte <span class="search-highlight">positive</span> <span class="search-highlight">selection</span> and differentiation by repression of Shh in another window
Includes: Supplementary data