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Keywords: Polycomb group
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Journal Articles
Journal: Development
Development (2015) 142 (17): 2876–2887.
Published: 1 September 2015
... that an exquisitely regulated cascade of transiently expressed transcription factors establishes initial gene expression patterns. Subsequently, these expression states are maintained or remembered by epigenetic cellular memory systems. Polycomb group (PcG) proteins and Trithorax group (TrxG) proteins are vital...
Journal Articles
Journal: Development
Development (2014) 141 (3): 526–537.
Published: 1 February 2014
... model for bivalency. In contrast, we propose that Mll2 is the pioneer trimethyltransferase for promoter definition in the naïve epigenome and that Polycomb group action on bivalent promoters blocks the premature establishment of active, Set1C-bound, promoters. References Akkers R. C...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2012) 139 (21): 4083–4093.
Published: 1 November 2012
... that the epidermis dramatically attenuates MRC expression during ageing but restores gene activity when budding commences. During budding and ageing, the nuclear gene Eed (a polycomb group component) was activated and inactivated in a pattern similar to that observed in MRCs. In buds, RNA interference (RNAi) of Eed...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (14): 2566–2575.
Published: 15 July 2012
...Julia Engelhorn; Julia J. Reimer; Iris Leuz; Ulrike Göbel; Bruno Huettel; Sara Farrona; Franziska Turck In a reverse genetics screen based on a group of genes enriched for development-related Polycomb group targets in the apex (DPAs), we isolated DPA4 as a novel regulator of leaf margin shape. T...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2006) 133 (7): 1231–1240.
Published: 1 April 2006
...Jian Wang; Ching-Hsien J. Lee; Suewei Lin; Tzumin Lee Polyhomeotic (Ph), which forms complexes with other Polycomb-group (PcG)proteins, is widely required for maintenance of cell identity by ensuring differential gene expression patterns in distinct types of cells. Genetic mosaic screens in adult...
Journal Articles
Journal Articles
Journal: Development
Development (2004) 131 (6): 1389–1400.
Published: 15 March 2004
...Karine Narbonne; Florence Besse; Jeanine Brissard-Zahraoui; Anne-Marie Pret; Denise Busson The polyhomeotic ( ph ) gene of Drosophila is a member of the Polycomb group ( Pc -G) genes, which are required for maintenance of a repressed state of homeotic gene transcription, which stabilizes cell...
Journal Articles
Journal: Development
Development (2002) 129 (6): 1339–1343.
Published: 15 March 2002
... activities of Zeste and GAGA are an essential component of the mechanism that chooses which maintenance system is to be targeted to a given promoter. *Author for correspondence (e-mail: mdbiggin@lbl.gov ) 17 12 2001 © 2002. 2002 Polycomb group Trithorax group Homeotic Zeste GAGA...
Journal Articles
Journal Articles
Journal: Development
Development (2001) 128 (6): 993–1004.
Published: 15 March 2001
... remain off in all the descendent cells, even though the Gap repressors are no longer present. This phenomenon of heritable silencing depends on proteins of the Polycomb Group (PcG) and on cis -acting Polycomb response elements (PREs) in the Hox gene loci. We have removed individual PcG proteins from...
Journal Articles
Journal Articles
Journal: Development
Development (1998) 125 (20): 4055–4066.
Published: 15 October 1998
...Kryn Stankunas; Joel Berger; Chris Ruse; Donald A. R. Sinclair; Filippo Randazzo; Hugh W. Brock ABSTRACT The Polycomb group of genes in Drosophila are homeotic switch gene regulators that maintain homeotic gene repression through a possible chromatin regulatory mechanism. The Enhancer of Polycomb...
Journal Articles
Journal Articles
Journal: Development
Development (1998) 125 (13): 2451–2456.
Published: 1 July 1998
... and mes-6 . The proteins encoded by mes-2 and mes-6 have been shown to be related to the Polycomb Group of transcriptional repressors (Holdeman, R., Nehrt, S. and Strome, S. (1998). Development 125, 2457-2467; Korf, I., Fan, F. and Strome, S. (1998). Development 125, 2469-2478). These results suggest...
Journal Articles
Journal Articles
Journal: Development
Development (1998) 125 (13): 2469–2478.
Published: 1 July 1998
...-6 gene is in an unusual operon, the second example of this type of operon in C. elegans , and encodes the nematode homolog of Extra sex combs, a WD-40 protein in the Polycomb group in Drosophila. mes-2 encodes another Polycomb group protein (see paper by Holdeman, R., Nehrt, S. and Strome, S. (1998...
Journal Articles