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Keywords: Polycomb group
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Journal Articles
Journal: Development
Development (2015) 142 (17): 2876–2887.
Published: 1 September 2015
.... , Wang , L. , Wang , H. , Xia , L. , Erdjument-Bromage , H. , Tempst , P. , Jones , R. S. and Zhang , Y. ( 2002 ). Role of histone H3 lysine 27 methylation in Polycomb-group silencing . Science   298 , 1039 - 1043 . 10.1126/science.1076997 Cech , T. R...
Journal Articles
Journal: Development
Development (2014) 141 (3): 526–537.
Published: 1 February 2014
... model for bivalency. In contrast, we propose that Mll2 is the pioneer trimethyltransferase for promoter definition in the naïve epigenome and that Polycomb group action on bivalent promoters blocks the premature establishment of active, Set1C-bound, promoters. To compensate for differences...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (20): 4182–4192.
Published: 15 October 2013
...Kristel M. Dorighi; John W. Tamkun Members of the Polycomb group of repressors and trithorax group of activators maintain heritable states of transcription by modifying nucleosomal histones or remodeling chromatin. Although tremendous progress has been made toward defining the biochemical...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (21): 4083–4093.
Published: 1 November 2012
... that the epidermis dramatically attenuates MRC expression during ageing but restores gene activity when budding commences. During budding and ageing, the nuclear gene Eed (a polycomb group component) was activated and inactivated in a pattern similar to that observed in MRCs. In buds, RNA interference (RNAi) of Eed...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (14): 2566–2575.
Published: 15 July 2012
...Julia Engelhorn; Julia J. Reimer; Iris Leuz; Ulrike Göbel; Bruno Huettel; Sara Farrona; Franziska Turck In a reverse genetics screen based on a group of genes enriched for development-related Polycomb group targets in the apex (DPAs), we isolated DPA4 as a novel regulator of leaf margin shape. T...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (24): 4131–4139.
Published: 15 December 2008
... properties of Polycomb-group proteins, whereas their activities are generally opposed by the trithorax group. Both groups modify chromatin structure, but how their opposing activities are targeted to allow differential maintenance remains a mystery. Here, we identify a strong pairing-sensitive silencing (PSS...
Journal Articles
Journal: Development
Development (2007) 134 (6): 1091–1099.
Published: 15 March 2007
...Bruno Bello; Niklaus Holbro; Heinrich Reichert Genes of the Polycomb group (PcG) are part of a cellular memory system that maintains appropriate inactive states of Hox gene expression in Drosophila . Here, we investigate the role of PcG genes in postembryonic development of the Drosophila CNS. We...
Journal Articles
Journal: Development
Development (2006) 133 (7): 1231–1240.
Published: 1 April 2006
...Jian Wang; Ching-Hsien J. Lee; Suewei Lin; Tzumin Lee Polyhomeotic (Ph), which forms complexes with other Polycomb-group (PcG)proteins, is widely required for maintenance of cell identity by ensuring differential gene expression patterns in distinct types of cells. Genetic mosaic screens in adult...
Journal Articles
Journal: Development
Development (2005) 132 (16): 3753–3765.
Published: 15 August 2005
... mosaics of genes in the Polycomb group of Drosophila melanogaster. Genetics 140 , 231 -243. Strub, S. ( 1977 ). Localization of the cells capable of transdetermiantion in a specific region of the male foreleg disc of Drosophila. Wilhelm Roux's Arch. Dev. Biol. 182 , 69 -74. Sustar...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (6): 1389–1400.
Published: 15 March 2004
...Karine Narbonne; Florence Besse; Jeanine Brissard-Zahraoui; Anne-Marie Pret; Denise Busson The polyhomeotic ( ph ) gene of Drosophila is a member of the Polycomb group ( Pc -G) genes, which are required for maintenance of a repressed state of homeotic gene transcription, which stabilizes cell...
Journal Articles
Journal: Development
Development (2002) 129 (6): 1339–1343.
Published: 15 March 2002
... to initiate the maintenance phase of repression. The dual activities of Zeste and GAGA could be a key to understanding this fascinating regulatory mechanism. Polycomb group Trithorax group Homeotic Zeste GAGA Drosophila The mRNA expression patterns of the Hox or homeotic genes...
Journal Articles
Journal: Development
Development (2001) 128 (17): 3371–3379.
Published: 1 September 2001
...Anna Birve; Aditya K. Sengupta; Dirk Beuchle; Jan Larsson; James A. Kennison; Åsa Rasmuson-Lestander; Jürg Müller In both Drosophila and vertebrates, spatially restricted expression of HOX genes is controlled by the Polycomb group (PcG) repressors. Here we characterize a novel Drosophila PcG...