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Keywords: Planarians
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Journal Articles
Journal: Development
Development (2019) 146 (17): dev167684.
Published: 11 September 2019
...Mario Ivankovic; Radmila Haneckova; Albert Thommen; Markus A. Grohme; Miquel Vila-Farré; Steffen Werner; Jochen C. Rink ABSTRACT Planarians are a group of flatworms. Some planarian species have remarkable regenerative abilities, which involve abundant pluripotent adult stem cells. This makes these...
Journal Articles
Journal: Development
Development (2016) 143 (22): 4149–4160.
Published: 15 November 2016
...Miquel Sureda-Gómez; José M. Martín-Durán; Teresa Adell The β-catenin-dependent Wnt pathway exerts multiple context-dependent roles in embryonic and adult tissues. In planarians, β-catenin-1 is thought to specify posterior identities through the generation of an anteroposterior gradient. However...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (6): 1062–1072.
Published: 15 March 2015
...Jared H. Owen; Daniel E. Wagner; Chun-Chieh Chen; Christian P. Petersen; Peter W. Reddien Regeneration requires that the identities of new cells are properly specified to replace missing tissues. The Wnt signaling pathway serves a central role in specifying posterior cell fates during planarian...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (6): 1197–1208.
Published: 15 March 2014
...Alexander Y. T. Lin; Bret J. Pearson During adult homeostasis and regeneration, the freshwater planarian must accomplish a constant balance between cell proliferation and cell death, while also maintaining proper tissue and organ size and patterning. How these ordered processes are precisely...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (23): 4691–4702.
Published: 01 December 2013
...Martis W. Cowles; David D. R. Brown; Sean V. Nisperos; Brianna N. Stanley; Bret J. Pearson; Ricardo M. Zayas In contrast to most well-studied model organisms, planarians have a remarkable ability to completely regenerate a functional nervous system from a pluripotent stem cell population. Thus...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (4): 719–729.
Published: 15 February 2013
...Chun-Chieh G. Chen; Irving E. Wang; Peter W. Reddien Planarian regeneration involves regionalized gene expression that specifies the body plan. After amputation, planarians are capable of regenerating new anterior and posterior poles, as well as tissues polarized along the anterior-posterior...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (6): 905–910.
Published: 15 March 2009
...Teresa Adell; Emili Salò; Michael Boutros; Kerstin Bartscherer Planarians can regenerate a whole animal from only a small piece of their body, and have become an important model for stem cell biology. To identify regenerative processes dependent on Wnt growth factors in the planarian Schmidtea...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (7): 1215–1221.
Published: 01 April 2008
... pathway in planarians, flatworms renowned for their extraordinary morphological plasticity. Canonical Wnt signalling is an evolutionarily conserved mechanism to confer polarity during embryonic development, specifying the anteroposterior (AP) axis in most bilaterians and the dorsoventral (DV) axis in...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (8): 1863–1874.
Published: 15 April 2005
... of the stem cell biology is emerging. Planarian regeneration, which is based upon totipotent stem cells present in the adult – the so-called neoblasts– provides a unique opportunity to study in vivo the molecular program that defines a stem cell. The choice of a stem cell to self-renew or...
Journal Articles
Journal: Development
Development (2002) 129 (6): 1423–1434.
Published: 15 March 2002
...David Pineda; Leonardo Rossi; Renata Batistoni; Alessandra Salvetti; Maria Marsal; Vittorio Gremigni; Alessandra Falleni; Javier Gonzalez-Linares; Paolo Deri; Emili Saló We report the presence of two Pax6 -related genes, Pax6A and Pax6B , which are highly conserved in two planarian species Dugesia...