...-FORMED1 (PIN1) is altered in vcc developing cotyledons and that overexpression of PIN1-GFP partially rescues vascular defects of vcc in a dosage-dependent manner. Genetic analyses suggest that VCC and PINOID (PID), a kinase that regulates PIN1 polarity, are both required for PIN1-mediated control...

... auxin biosynthesis, and is required for proper repolarisation of PIN1 auxin efflux facilitators and reprogramming of vascular identity in aerial organs. The PLT-CUC2 module is strictly required for regeneration of leaf vasculature, but is not essential for the normal development of closed vein loops...

... (PIN1). Here, we show that in the triple transcription factor mutant cytokinin response factor 2 ( crf2 ) crf3 crf6 both pistil length and ovule number were reduced. PIN1 expression was also lower in the triple mutant and the phenotypes could not be rescued by exogenous cytokinin application. pin1...

... acids, specific competitors of B, phenocopies the Arabidopsis thaliana rootless pattern mutant monopteros. At least in part, this is caused by phenylboronic acid (PBA)-induced internalisation of the membrane-localised auxin efflux carrier PINFORMED1 (PIN1) in the early embryo. PIN1 internalisation...

... precise phyllotactic patterns. The mechanism is based on the active cellular transport of the phytohormone auxin by cellular influx and efflux carriers, such as AUX1 and PIN1. Their important role in phyllotaxis is evident from mutant phenotypes, but their exact roles in space and time are difficult...

... feedback mechanism involved in setting the positional boundary. * Author for correspondence ( [email protected] ) Competing interests statement The authors declare no competing financial interests. 8 11 2012 © 2013. Published by The Company of Biologists Ltd PIN1 Leaf...

... and shoot growth in Arabidopsis . In the shoot, COP1 regulates shoot-to-root auxin transport by controlling the transcription of the auxin efflux carrier gene PIN - FORMED1 ( PIN1 ), thus appropriately tuning shoot-derived auxin levels in the root. This in turn directly influences root elongation and adapts...

... in repressing blade outgrowth, entire plants show defects in leaflet initiation as well. This defect could result from feedback between the response to auxin and auxin transport during leaf development. The expression of PIN1:GFP is less refined in the entire background, and misregulation of SlPIN1 might...

... phenotype and triggered a hypocotyl gain-of-function phenotype, similar to strong overexpressors of full length BRX. Therefore, although BRX activity is required in the nucleus,excess activity interferes with normal development. Finally, similar to the PIN-FORMED 1 (PIN1) auxin efflux carrier, BRX...

... been suggested to control PIN1 polarity in cotyledon primordia. MAB4 / ENP encodes a novel protein,which belongs to the NON-PHOTOTROPIC HYPOCOTYL 3 (NPH3) family thought to function as a signal transducer in phototropism and control lateral translocation of auxin. MAB4 / ENP mRNA was detected...

.... However, analysis of pid enp stm triple mutants shows that ectopic activity of STM does not appear to cause cotyledon obliteration. This is exclusively caused by enp in concert with pid . In pinoid embryos, reversal of polarity of the PIN1 auxin transport facilitator in the apex is only occasional...

...Masahiko Furutani; Teva Vernoux; Jan Traas; Takehide Kato; Masao Tasaka; Mitsuhiro Aida In dicotyledonous plants, two cotyledons are formed at bilaterally symmetric positions in the apical region of the embryo. Single mutations in the PIN-FORMED1 ( PIN1 ) and PINOID ( PID )genes, which mediate...

... * , † pin1-1 (15) 2.57±0.19 * 2.36±0.10 * 0.95±0.04 * 4.63±0.56 pin1-1 fkd1 (15) 2.69±0.10 * , † 2.88±0.09 ‡ 1.08±0.03 * , † , ‡ 5.81±0.33 * aux1-7 (38) 2.47±0.05 * 3.07±0.08 * 1.24±0.02 5.96±0.27 * aux1-7 fkd1 (37) 2.41±0.06 * 3.08±0.08...

... and after their migration to the gonads from 8.5 to 13.5 days post coitum (dpc). We show that a peptidyl-prolyl isomerase, Pin1, is involved in the regulation of mammalian PGC proliferation. We discovered that both the male and female Pin1 -/- mice had profound fertility defects. Investigation...

... this patterning process, we analyzed functions of two Arabidopsis genes, PIN-FORMED1 ( PIN1 ) and MONOPTEROS ( MP ), encoding a putative auxin efflux carrier and a transcription factor thought to mediate auxin signaling, respectively. The corresponding mutants show similar defects in apical patterning, including...

...Teva Vernoux; Jocelyne Kronenberger; Olivier Grandjean; Patrick Laufs; Jan Traas ABSTRACT The process of organ positioning has been addressed, using the pin-formed 1 ( pin1 ) mutant as a tool. PIN1 is a transmembrane protein involved in auxin transport in Arabidopsis . Loss of function severely...

... organ on the vascular pattern. Mutations in the genes MP and LOP1 result in vascular abnormalities nearly reciprocal to those of pin1 mutants, indicating unrelated defects ( Przemeck et al., 1996 ; Carland and McHale, 1996 ). We speculate that MP could affect the response of vascular cells...