... of two functional paralogues of csf1r in zebrafish. Mutant analysis indicates that the paralogues have shared, non-redundant roles in regulating osteoclast activity during the formation of the adult skeleton. csf1ra , however, has adopted unique roles in pigment cell patterning not seen in the second...

...Pooja Agarwal; Michael P. Verzi; Thuyen Nguyen; Jianxin Hu; Melissa L. Ehlers; David J. McCulley; Shan-Mei Xu; Evdokia Dodou; Joshua P. Anderson; Maria L. Wei; Brian L. Black Waardenburg syndromes are characterized by pigmentation and autosensory hearing defects, and mutations in genes encoding...

...Alejandro Barrallo-Gimeno; Jochen Holzschuh; Wolfgang Driever; Ela W. Knapik Neural crest progenitor cells are the main contributors to craniofacial cartilage and connective tissue of the vertebrate head. These progenitor cells also give rise to the pigment, neuronal and glial cell lineages...

...Robert D. Knight; Sreelaja Nair; Sarah S. Nelson; Ali Afshar; Yashar Javidan; Robert Geisler; Gerd-Joerg Rauch; Thomas F. Schilling The neural crest is a uniquely vertebrate cell type that gives rise to much of the craniofacial skeleton, pigment cells and peripheral nervous system, yet its...

...Patricia J. Wittkopp; John R. True; Sean B. Carroll Body coloration affects how animals interact with the environment. In insects, the rapid evolution of black and brown melanin patterns suggests that these are adaptive traits. The developmental and molecular mechanisms that generate these pigment...