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Keywords: Pierre-Robin sequence
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Journal Articles
Inactivation of LAR family phosphatase genes Ptprs and Ptprf causes craniofacial malformations resembling Pierre-Robin sequence
Available to Purchase
Journal:
Development
Development (2013) 140 (16): 3413–3422.
Published: 15 August 2013
... (small and deep tongue), a phenotype closely resembling Pierre-Robin sequence in humans. We show that jaw bone and cartilage patterning occurs aberrantly in LAR family phosphatase-deficient embryos and that the mandibular arch harbors a marked decrease in cell proliferation. Analysis of signal...
Includes: Supplementary data
